pestalotiopsin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pestalotiopsin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	10472425
MeSH ID	M0393176

Synonyms (1)

Synonym
pestalotiopsin a

Research Excerpts

Overview

Pestalotiopsin A is a structurally unique, caryophyllene-type sesquiterpene. It has shown immunosuppressive activity and cytotoxicity.

Excerpt	Reference	Relevance
"Pestalotiopsin A is a structurally unique, caryophyllene-type sesquiterpene which has shown immunosuppressive activity and cytotoxicity in preliminary assays. "	( The first synthetic studies on pestalotiopsin A. A stereocontrolled approach to the functionalised bicyclic core. Couché, E; Edmonds, DJ; Johnston, D; Muir, KW; Procter, DJ, 2003)	2.05

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (90.91)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (9.09)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.87

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	11.87 (24.57)
Research Supply Index	2.48 (2.92)
Research Growth Index	4.36 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (11.87)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (9.09%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (90.91%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
cyclopropane cyclopropane : A cycloalkane composed of three carbon atoms to form a ring.	2.04	1	cycloalkane; cyclopropanes	inhalation anaesthetic
3-hydroxybutanal [no description available]	2.05	1
n-heptane Heptanes: Seven-carbon alkanes with the formula C7H16.. heptane : A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (Pinus jeffreyi).	2.01	1	alkane; volatile organic compound	non-polar solvent; plant metabolite
palladium Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.	2.05	1	metal allergen; nickel group element atom; platinum group metal atom
samarium Samarium: An element of the rare earth family of metals. It has the atomic symbol Sm, atomic number 62, and atomic weight 150.36. The oxide is used in the control rods of some nuclear reactors.	2.7	3	f-block element atom; lanthanoid atom
zirconium Zirconium: A rather rare metallic element with atomic number 40, atomic weight 91.224, and symbol Zr.	2.03	1	titanium group element atom
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	3.41	1
lupeol [no description available]	3.41	1	pentacyclic triterpenoid; secondary alcohol	anti-inflammatory drug; plant metabolite
aglafoline aglafoline: a platelet activating factor antagonist; structure given in first source; isolated from Aglaia elliptifolia. aglafolin : A heterotricyclic compound based on a 2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan framework substituted by hydroxy groups at positions C-1 and C-8b, a methoxycarbonyl group at C-2, a phenyl group at C-3, a 4-methoxyphenyl group at C-3a and methoxy groups at C-6 and C-8. A platelet aggregation inhibitor found in Aglaia elliptifolia and Aglaia odorata.	3.41	1	methyl ester; organic heterotricyclic compound	metabolite; platelet aggregation inhibitor
steviol steviol: aglucon of stevioside; RN given refers to (4alpha)-isomer. steviol : An ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group.	3.41	1	bridged compound; ent-kaurane diterpenoid; monocarboxylic acid; tertiary allylic alcohol; tetracyclic diterpenoid	antineoplastic agent
stilbenes Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.	3.41	1	stilbene
sesquiterpenes [no description available]	4.93	11
7-epiclusianone 7-epiclusianone: from Rheedia gardneriana; structure in first source. 7-epiclusianone : An enone that is a tetraprenyl benzophenone derivative isolated from Rheedia gardneriana and Garcinia brasiliensis. It exhibits anti-allergic, antibacterial, trypanocidal and vasodilating activities.	3.41	1
goniomitine goniomitine: from root bark of Gonioma malagasy; structure in first source	3.41	1	monoterpenoid indole alkaloid

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