| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
9,10-dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene: Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.. 7,12-dimethyltetraphene : A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke. | 1.98 | 1 | 0 | ortho-fused polycyclic arene;
tetraphenes | carcinogenic agent |
buserelin
Buserelin: A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications. | 3.78 | 3 | 0 | oligopeptide | |
folligen
[no description available] | 4 | 4 | 0 | | |
gonadotropin-releasing hormone
relisorm L: Gonadotropin-Releasing Hormone analog. gonadorelin : A ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. | 1.95 | 1 | 0 | oligopeptide;
peptide hormone | gonadotropin releasing hormone agonist |
leuprolide
Leuprolide: A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.. leuprolide : An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. | 1.95 | 1 | 0 | oligopeptide | anti-estrogen;
antineoplastic agent;
gonadotropin releasing hormone agonist |
goserelin
Goserelin: A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer. | 2.38 | 2 | 0 | organic molecular entity | |
trelstar
Triptorelin Pamoate: A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE with D-tryptophan substitution at residue 6. | 1.98 | 1 | 0 | | |
deslorelin
deslorelin: Ovuplant is tradename for a short-term-release implant containing deslorelin acetate; RN given refers to D-isomer; RN for cpd without isomeric designation not avail 12/90 | 1.95 | 1 | 0 | oligopeptide | |
1-ac-trp-2-(4-cl-phe)-3-trp-6-lys-10-alanh2-lhrh
MI 1544: LHRH antagonist | 1.98 | 1 | 0 | | |
lhrh, phe(6)-
LHRH, Phe(6)-: RN given refers to (D)-isomer | 1.95 | 1 | 0 | | |