Page last updated: 2024-11-13
lhrh, phe(6)-
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
LHRH, Phe(6)-: RN given refers to (D)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 25079034 |
| CHEMBL ID | 3249402 |
| SCHEMBL ID | 11678163 |
| MeSH ID | M0106158 |
Synonyms (10)
| Synonym |
|---|
| gonavet |
| 6-phe-lhrh |
| lhrh, phenylalanine(6)- |
| lhrh, phe(6)- |
| 57521-78-5 |
| d-phe(6)-gnrh |
| gnrh, phe(6)- |
| CHEMBL3249402 |
| SCHEMBL11678163 |
| DTXSID50206131 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1145199 | Induction of FSH release in ovariectomized estrogen/progesterone-treated rat at 100 ng, sc measured after 15 mins to 60 hrs post dose by RIA relative to LH-RH | 1976 | Journal of medicinal chemistry, Mar, Volume: 19, Issue:3 | Analogs of luteinizing hormone-releasing hormone with increased biological activity produced by D-amino acid substitutions in position 6. |
| AID1136745 | Ovulation-inducing activity in androgen-sterilized constant-estrus rat at 0.01 ug, iv | 1978 | Journal of medicinal chemistry, Oct, Volume: 21, Issue:10 | Synthesis and biological activity of highly active alpha-aza analogues of luliberin. |
| AID1145197 | Induction of luteinizing hormone release in ovariectomized estrogen/progesterone-treated rat at 100 ng, sc measured after 15 mins to 60 hrs post dose by RIA relative to LH-RH | 1976 | Journal of medicinal chemistry, Mar, Volume: 19, Issue:3 | Analogs of luteinizing hormone-releasing hormone with increased biological activity produced by D-amino acid substitutions in position 6. |
| AID1136743 | Ovulation-inducing activity in androgen-sterilized constant-estrus rat at 0.005 ug, iv | 1978 | Journal of medicinal chemistry, Oct, Volume: 21, Issue:10 | Synthesis and biological activity of highly active alpha-aza analogues of luliberin. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.17
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.17) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||