Page last updated: 2024-12-08
ll-z 1271alpha
Description
Research Excerpts
Clinical Trials
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Bioassays
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Description
LL-Z 1271alpha: C(16) terpenoid lactone metabolite from Acrostalagmus; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 301929 |
CHEMBL ID | 480480 |
SCHEMBL ID | 7497165 |
MeSH ID | M0061073 |
Synonyms (26)
Synonym |
---|
ll z1271d |
nsc180975 |
nsc-180975 |
antibiotic ll-z1271a |
ll z1271.alpha. |
antibiotic ll-z 1271.alpha. |
4h,3',4':4,5]naphtho[2,1-c]pyran-4,9-dione, 1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-, [3as-(3a.alpha.,5a.alpha.,7.alpha.,10b.beta.,10c.alpha.)]- |
4h,3',4':4,5]naphtho[2,1-c]pyran-4,9-dione, 1,2,3,3a,5a.beta.,7,10b,10c.beta.-octahydro-7.beta.-methoxy-3a.beta.,10b.alpha.-dimethyl-, (-)- |
23660-12-0 |
ll-z 1271.alpha. |
antibiotic ll z1271.alpha. |
ll-z 1271alpha |
CHEMBL480480 |
ll-z 1271alpha; 4h,9h-furo(2',3',4':4,5)naphtho(2,1-c)pyran-4,9-dione, 1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-, (3as-(3aalpha,5aalpha,7alpha,10bbeta,10calpha))- |
pr 1387 |
4h,9h-furo(2',3',4':4,5)naphtho(2,1-c)pyran-4,9-dione, 1,2,3,3a,5abeta,7,10b,10cbeta-octahydro-7beta-methoxy-3abeta,10balpha-dimethyl-, (-)- |
7-methoxy-3a,10b-dimethyl-1,2,3,3aalpha,5aalpha,7,10bbeta,10calpha-octahydro-4h,9h-furo(2,3',4':4,5)naphtho(2,1-c)pyran-4,9-dione |
(3as-(3aalpha,5aalpha,7alpha,10bbeta,10calpha))-1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-4h,9h-furo(2',2',4':4,5-)naphtho(2,1-c)pyran-4,9-dione |
oidiolactone b |
ll-z1271 |
nsc 180975 |
ll-z1271alpha |
SCHEMBL7497165 |
(3as,3a1r,5ar,7s,10bs)-7-methoxy-3a,10b-dimethyl-1,2,3,3a,3a1,5a,7,10b-octahydro-4h,9h-isobenzofuro[7,1-fg]isochromene-4,9-dione |
(1s,6s,9r,12s,16r)-6-methoxy-1,12-dimethyl-5,10-dioxatetracyclo[7.6.1.02,7.012,16]hexadeca-2,7-diene-4,11-dione |
AKOS040753357 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (60)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1100999 | Stimulation of germination of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100991 | Inhibition of germination of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101006 | Stimulation of root length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100993 | Inhibition of shoot length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101005 | Stimulation of shoot length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398533 | Cytotoxicity against human NCI-H460 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1100972 | Inhibition of shoot length of Lepidium sativum at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100983 | Inhibition of root length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398532 | Cytotoxicity against human SF268 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1100996 | Stimulation of shoot length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101014 | Stimulation of shoot length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100984 | Inhibition of shoot length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100975 | Inhibition of shoot length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398530 | Cytotoxicity against human BxPC3 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1101012 | Stimulation of root length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101004 | Stimulation of germination of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100987 | Inhibition of shoot length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100990 | Inhibition of shoot length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100976 | Inhibition of germination of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101001 | Stimulation of germination of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID381169 | Herbicidal activity against Chlorella fusca at 10 mg/mL by agar diffusion test | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata |
AID1100992 | Inhibition of root length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398528 | Antimicrobial activity against Candida albicans by broth microdilution method | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1100986 | Inhibition of root length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398535 | Cytotoxicity against human DU145 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1101011 | Stimulation of germination of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101009 | Stimulation of root length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100982 | Inhibition of germination of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100995 | Inhibition of root length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID381176 | Antibacterial activity against Bacillus megaterium at 10 mg/mL by agar diffusion test | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata |
AID1101002 | Stimulation of root length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101007 | Stimulation of germination of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101008 | Stimulation of shoot length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398527 | Antimicrobial activity against Cryptococcus neoformans by broth microdilution method | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1100988 | Inhibition of germination of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100978 | Inhibition of shoot length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100980 | Inhibition of root length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100973 | Inhibition of root length of Lepidium sativum at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100971 | Inhibition of germination of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101013 | Stimulation of germination of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100970 | Inhibition of root length of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398529 | Cytotoxicity against mouse P388 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID398534 | Cytotoxicity against human KM20L2 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1100979 | Inhibition of germination of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101000 | Stimulation of root length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100989 | Inhibition of root length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID381172 | Antifungal activity against Ustilago violacea at 10 mg/mL by agar diffusion test | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata |
AID1100974 | Inhibition of germination of Lepidium sativum at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100997 | Stimulation of root length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100969 | Inhibition of shoot length of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101010 | Stimulation of shoot length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID398531 | Cytotoxicity against human MCF7 cells | 2003 | Journal of natural products, Feb, Volume: 66, Issue:2 | Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. |
AID1101015 | Stimulation of root length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100981 | Inhibition of shoot length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101016 | Stimulation of germination of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100994 | Inhibition of germination of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100977 | Inhibition of root length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100985 | Inhibition of germination of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1100998 | Stimulation of shoot length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
AID1101003 | Stimulation of shoot length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control | 2000 | Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7 | Natural and synthetic podolactones with potential use as natural herbicide models. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 5 (83.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.59
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.59) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |