Compounds > ll-z 1271alpha
Page last updated: 2024-12-08

ll-z 1271alpha

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Description

LL-Z 1271alpha: C(16) terpenoid lactone metabolite from Acrostalagmus; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID301929
CHEMBL ID480480
SCHEMBL ID7497165
MeSH IDM0061073

Synonyms (26)

Synonym
ll z1271d
nsc180975
nsc-180975
antibiotic ll-z1271a
ll z1271.alpha.
antibiotic ll-z 1271.alpha.
4h,3',4':4,5]naphtho[2,1-c]pyran-4,9-dione, 1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-, [3as-(3a.alpha.,5a.alpha.,7.alpha.,10b.beta.,10c.alpha.)]-
4h,3',4':4,5]naphtho[2,1-c]pyran-4,9-dione, 1,2,3,3a,5a.beta.,7,10b,10c.beta.-octahydro-7.beta.-methoxy-3a.beta.,10b.alpha.-dimethyl-, (-)-
23660-12-0
ll-z 1271.alpha.
antibiotic ll z1271.alpha.
ll-z 1271alpha
CHEMBL480480
ll-z 1271alpha; 4h,9h-furo(2',3',4':4,5)naphtho(2,1-c)pyran-4,9-dione, 1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-, (3as-(3aalpha,5aalpha,7alpha,10bbeta,10calpha))-
pr 1387
4h,9h-furo(2',3',4':4,5)naphtho(2,1-c)pyran-4,9-dione, 1,2,3,3a,5abeta,7,10b,10cbeta-octahydro-7beta-methoxy-3abeta,10balpha-dimethyl-, (-)-
7-methoxy-3a,10b-dimethyl-1,2,3,3aalpha,5aalpha,7,10bbeta,10calpha-octahydro-4h,9h-furo(2,3',4':4,5)naphtho(2,1-c)pyran-4,9-dione
(3as-(3aalpha,5aalpha,7alpha,10bbeta,10calpha))-1,2,3,3a,5a,7,10b,10c-octahydro-7-methoxy-3a,10b-dimethyl-4h,9h-furo(2',2',4':4,5-)naphtho(2,1-c)pyran-4,9-dione
oidiolactone b
ll-z1271
nsc 180975
ll-z1271alpha
SCHEMBL7497165
(3as,3a1r,5ar,7s,10bs)-7-methoxy-3a,10b-dimethyl-1,2,3,3a,3a1,5a,7,10b-octahydro-4h,9h-isobenzofuro[7,1-fg]isochromene-4,9-dione
(1s,6s,9r,12s,16r)-6-methoxy-1,12-dimethyl-5,10-dioxatetracyclo[7.6.1.02,7.012,16]hexadeca-2,7-diene-4,11-dione
AKOS040753357
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (60)

Assay IDTitleYearJournalArticle
AID1100999Stimulation of germination of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100991Inhibition of germination of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101006Stimulation of root length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100993Inhibition of shoot length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101005Stimulation of shoot length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398533Cytotoxicity against human NCI-H460 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1100972Inhibition of shoot length of Lepidium sativum at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100983Inhibition of root length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398532Cytotoxicity against human SF268 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1100996Stimulation of shoot length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101014Stimulation of shoot length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100984Inhibition of shoot length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100975Inhibition of shoot length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398530Cytotoxicity against human BxPC3 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1101012Stimulation of root length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101004Stimulation of germination of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100987Inhibition of shoot length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100990Inhibition of shoot length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100976Inhibition of germination of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101001Stimulation of germination of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID381169Herbicidal activity against Chlorella fusca at 10 mg/mL by agar diffusion test1999Journal of natural products, Sep, Volume: 62, Issue:9
Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata
AID1100992Inhibition of root length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398528Antimicrobial activity against Candida albicans by broth microdilution method2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1100986Inhibition of root length of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398535Cytotoxicity against human DU145 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1101011Stimulation of germination of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101009Stimulation of root length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100982Inhibition of germination of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100995Inhibition of root length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID381176Antibacterial activity against Bacillus megaterium at 10 mg/mL by agar diffusion test1999Journal of natural products, Sep, Volume: 62, Issue:9
Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata
AID1101002Stimulation of root length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101007Stimulation of germination of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101008Stimulation of shoot length of Lepidium sativum at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398527Antimicrobial activity against Cryptococcus neoformans by broth microdilution method2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1100988Inhibition of germination of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100978Inhibition of shoot length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100980Inhibition of root length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100973Inhibition of root length of Lepidium sativum at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100971Inhibition of germination of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101013Stimulation of germination of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100970Inhibition of root length of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398529Cytotoxicity against mouse P388 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID398534Cytotoxicity against human KM20L2 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1100979Inhibition of germination of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101000Stimulation of root length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100989Inhibition of root length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID381172Antifungal activity against Ustilago violacea at 10 mg/mL by agar diffusion test1999Journal of natural products, Sep, Volume: 62, Issue:9
Biologically active secondary metabolites from fungi. 12.(1) oidiolactones A-F, labdane diterpene derivatives isolated from oidiodendron truncata
AID1100974Inhibition of germination of Lepidium sativum at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100997Stimulation of root length of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100969Inhibition of shoot length of Solanum lycopersicum (tomato) at 10 uM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101010Stimulation of shoot length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID398531Cytotoxicity against human MCF7 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus.
AID1101015Stimulation of root length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100981Inhibition of shoot length of Lactuca sativa cv. Roman (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101016Stimulation of germination of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100994Inhibition of germination of Hordeum vulgare (barley) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100977Inhibition of root length of Lactuca sativa cv. Nigra (lettuce) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100985Inhibition of germination of Solanum lycopersicum (tomato) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1100998Stimulation of shoot length of Triticum aestivum (wheat) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
AID1101003Stimulation of shoot length of Allium cepa (onion) at 0.1 mM after 5 days relative to untreated control2000Journal of agricultural and food chemistry, Jul, Volume: 48, Issue:7
Natural and synthetic podolactones with potential use as natural herbicide models.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.59

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.59 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.54 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.59)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.		210amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
nagilactone c
nagilactone C: norditerpene lactone isolated from leaves of Podocarpus; structure		2.0510
triasulfuron
triasulfuron : An N-sulfonylurea that is N-[o-(2-chloroethoxy)phenyl]sulfonylurea in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used to control broad-leaved weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life.		2101,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound		agrochemical;
herbicide
ConditionIndicatedRelationship StrengthStudiesTrials