Page last updated: 2024-11-12
hypoestoxide
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
hypoestoxide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11199742 |
| MeSH ID | M0395205 |
Synonyms (6)
| Synonym |
|---|
| 88498-46-8 |
| hypoestoxide |
| [(1r,3s,5s,8s,10s,12r,13s)-5,10,17,17-tetramethyl-14-methylidene-15-oxo-4,9-dioxatetracyclo[11.3.1.03,5.08,10]heptadecan-12-yl] acetate |
| (1r,3s,5s,8s,10s,12r,13s)-5,10,17,17-tetramethyl-14-methylene-15-oxo-4,9-dioxatetracyclo[11.3.1.03,5.08,10]heptadecan-12-yl acetate |
| hypoestoxide,hypoestes rosea |
| PD132594 |
Research Excerpts
Overview
Hypoestoxide (HE) is a diterpene isolated from Hypoestes rosea (Acanthaceae), a plant indigenous to Nigeria.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Hypoestoxide (HE) is a diterpene isolated from Hypoestes rosea (Acanthaceae), a plant indigenous to Nigeria. " | ( Plasmodium berghei: antiparasitic effects of orally administered hypoestoxide in mice. Adesomoju, AA; Cottam, HB; Nchekwube, EJ; Ojo-Amaize, EA; Okogun, JI; Oyemade, OA, 2007) | 2.02 |
Effects
| Excerpt | Reference | Relevance |
|---|---|---|
| "Hypoestoxide (HE) has been demonstrated as a NF-κB modulator, thereby acting as a potential anti-inflammatory and anti-cancer drug." | ( Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease. Adame, A; Chan, M; Cottam, H; Desplats, P; Kim, C; Mante, M; Masliah, E; Nchekwube, E; Ojo-Amaize, E; Okogun, J; Oyemade, O; Rockenstein, E; Spencer, B; Wrasidlo, W, 2015) | 2.58 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 19.89
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.89) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||