Page last updated: 2024-12-08
hre 664
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
HRE 664: synthetic penem antibiotic; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 147078 |
| SCHEMBL ID | 10395453 |
| MeSH ID | M0151074 |
Synonyms (9)
| Synonym |
|---|
| hre 664 |
| (5r,6s)-3-(4-carbamoylphenoxy)-6-[(1r)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
| 3-(4-carbamoylphenoxy)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylate |
| 105275-74-9 |
| 4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(4-(aminocarbonyl)phenoxy)-6-(1-hydroxyethyl)-7-oxo-, (5r-(5alpha,6alpha(r*)))- |
| hre-664 |
| SCHEMBL10395453 |
| 3-(4-carbamoylphenoxy)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
| DTXSID80909406 |
Research Excerpts
Overview
HRE 664 is a novel parenteral penem with a broad antimicrobial spectrum.
| Excerpt | Reference | Relevance |
|---|---|---|
| "HRE 664 is a novel parenteral penem with a broad antimicrobial spectrum. " | ( An in vitro evaluation of HRE 664, a novel penem antibiotic. Aldridge, KE; Barry, AL; Fuchs, PC; Jones, RN, 1988) | 2.02 |
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| "The pharmacokinetic and chemotherapeutic properties of the new penem antibiotic HRE 664 (Fig." | ( HRE 664, a new parenteral penem. II. Evaluation of the pharmacokinetic behavior and the chemotherapeutic activity in animals. Isert, D; Johnson, C; Klesel, N; Limbert, M; Schrinner, E; Seibert, G, 1987) | 1.94 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.25
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.25) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||