Compounds > gr 122222x
Page last updated: 2024-12-11

gr 122222x

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

GR 122222X: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5748227
MeSH IDM0234727

Synonyms (10)

Synonym
unii-nf9u2lvf79
gr122222x
l-alanyl-(3r)-3-hydroxy-l-prolyl-l-seryl-s-((2-carboxy-4,6-dihydroxy-3-methylphenyl)methyl)-l-cysteinyl-l-alanine (4-3)-lactone
nf9u2lvf79 ,
161161-54-2
l-alanine, l-alanyl-(3r)-3-hydroxy-l-prolyl-l-seryl-s-((2-carboxy-4,6-dihydroxy-3-methylphenyl)methyl)-l-cysteinyl-, (4-3)-lactone
gr 122222x
[(2s)-2-[[(2s)-2-aminopropanoyl]-[(2r)-2-[[(2s)-3-hydroxy-2-[[(2s,3r)-3-hydroxypyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylidenepropanoyl]amino]propanoyl] 3,5-dihydroxy-2-methyl-6-(sulfanylmethyl)benzoate
DTXSID50167071
(s)-2-((s)-2-amino-n-((r)-2-((s)-3-hydroxy-2-((2s,3r)-3-hydroxypyrrolidine-2-carboxamido)propanamido)-3-thioxopropanoyl)propanamido)propanoic 3,5-dihydroxy-2-(mercaptomethyl)-6-methylbenzoic anhydride
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.60

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.60 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.39 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.60)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
coumarin
2H-chromen-2-one: coumarin derivative		2.0110coumarinsfluorescent dye;
human metabolite;
plant metabolite
adenylyl imidodiphosphate
Adenylyl Imidodiphosphate: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.		1.9910adenosine 5'-phosphate
ro 09-1437
cyclothialidine: a DNA gyrase inhibitor; isolated from Streptomyces filipinensis; MF C26-H35-N5-O12-S; structure in first source		2.0610peptide
novobiocin
Novobiocin: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189). novobiocin : A coumarin-derived antibiotic obtained from Streptomyces niveus.		2.9140carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.		2.0110benzenes;
hydroxycoumarin;
methyl ketone
dihydronovobiocin
dihydronovobiocin: high affinity for DNA gyrase B; structure given		2.0110
ConditionIndicatedRelationship StrengthStudiesTrials