Page last updated: 2024-11-05
formamidoxime
Description
Formamidoxime is a colorless, crystalline solid with the molecular formula CH4N2O. It is a derivative of formamide, in which the carbonyl group is replaced by an oxime group. Formamidoxime has been studied for its potential applications in various fields, including organic synthesis, pharmaceuticals, and material science.
Its synthesis is achieved through the reaction of formamide with hydroxylamine in the presence of a base, such as sodium hydroxide or potassium hydroxide. The reaction typically takes place in aqueous or alcoholic solution at elevated temperatures.
Formamidoxime has been investigated for its biological effects. It has shown anti-inflammatory, antioxidant, and anticancer activities in preliminary studies. Its mechanism of action is believed to involve the inhibition of inflammatory mediators and the modulation of cellular redox signaling pathways. However, further research is needed to fully understand its biological effects and potential therapeutic applications.
Formamidoxime is also a versatile intermediate in organic synthesis. It can be used to prepare a wide range of organic compounds, including heterocycles, amides, and nitriles. Its reactivity arises from the presence of the oxime group, which can undergo various chemical transformations, such as reduction, oxidation, and nucleophilic attack.
In addition to its chemical and biological properties, formamidoxime has shown promise as a material precursor for the synthesis of polymers and other functional materials. Its ability to form strong hydrogen bonds and its high polarity make it a potential candidate for developing advanced materials with desirable properties.
The study of formamidoxime continues to be an active area of research due to its diverse applications and potential benefits. Researchers are investigating its synthesis, reactivity, biological effects, and applications in various fields. Further research is expected to unveil new insights into the properties and potential of this intriguing compound.'
formamidoxime: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 12227 |
| MeSH ID | M0041362 |
Synonyms (9)
| Synonym |
|---|
| formamidoxime |
| 624-82-8 |
| FT-0632630 |
| aminonitrone |
| BCP31141 |
| formamidoxim;isuretin;n'-hydroxyimidoformamide |
| cid 12227 |
| n inverted exclamation mark -hydroxyformimidamide |
| SY086195 |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 50.45
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 50.45 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 4.32 (4.65) | | Search Engine Demand Index | 76.15 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |