Compounds > fd 891
Page last updated: 2024-11-11

fd 891

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

FD 891: an 18-membered macrolide with an epoxide ring at C8 and C9; the epoxide may play an important role in its cytocidal activity; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6444177
MeSH IDM0240701

Synonyms (5)

Synonym
fd 891
9,19-dioxabicyclo(16.1.0)nonadeca-4,6,12,14-tetraen-8-one, 10-(4,6-dihydroxy-8-methoxy-1,5,7-trimethylnonyl)-2,17-dihydroxy-3,5,7-trimethyl-
142383-53-7
fd-891
(1s,2s,3r,4z,6z,10s,12z,14z)-10-[(5s,6r,7r,8s,9s)-5,7-dihydroxy-9-methoxy-6,8-dimethyldecan-2-yl]-2,17-dihydroxy-3,5,7-trimethyl-9,19-dioxabicyclo[16.1.0]nonadeca-4,6,12,14-tetraen-8-one
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.78

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.78 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index4.71 (4.65)
Search Engine Demand Index24.97 (26.88)
Search Engine Supply Index3.00 (0.95)

This Compound (22.78)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (6.25%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (93.75%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
3-hydroxybutanal
[no description available]		2.110
alkenes
[no description available]		2.0310
thaxtomine a
thaxtomine A: a phytotoxin produced by Streptomyces scabies; RN given for (3R-trans)-isomer; structure in first source		3.1910
concanamycin b
concanamycin B: from Streptomyces diastatochromogenes S-45; structure given in first source		3.1910
concanamycin a
concanamycin A: from Streptomyces diastatochromogenes S-45; inhibits vacuolar H+ ATPase. concanamycin A : A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group.		3.5420carbamate ester;
concanamycin		antifungal agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
metabolite
am 2604a
virustomycin A: from Streptomyces sp. AM-2604		2.610
cytochrome c-t
Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.		2.0510
borrelidin
treponemycin: isolated from Streptomyces albovinaceous; active against Treponema hyodysenteriae. borrelidin : A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties.		3.1910aliphatic nitrile;
diol;
macrolide;
monocarboxylic acid;
secondary alcohol		antifungal agent;
antimalarial;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite
ConditionIndicatedRelationship StrengthStudiesTrials