chiriquitoxin: natural analog of tetrodotoxin isolated from Central American frog Atelopus chiriquensis [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 162174 |
| MeSH ID | M0065236 |
| Synonym |
|---|
| chiridquitoxin |
| chiriquitoxin |
| 61132-15-8 |
| 11-[amino(carboxy)methyl]tetrodotoxin |
| DTXSID30976648 |
| 2-amino-3-(3-amino-5,9,12,13,14-pentahydroxy-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-14-yl)-3-hydroxypropanoic acid |
Chiriquitoxin is a new, natural analog of tetrodotoxin. It differs only in having the -CH2OH on C-6 replaced with an unidentified group of 104 mass units.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Chiriquitoxin is a new, natural analog of tetrodotoxin, differing only in having the -CH2OH on C-6 replaced with an unidentified group of 104 mass units. " | ( Tetrodotoxin, saxitoxin, chiriquitoxin: new perspectives on ionic channels. Kao, CY, 1981) | 2.01 |
| "Chiriquitoxin is a new natural analog of tetrodotoxin in which the -CH2OH group on C6 has been replaced with a yet unidentified group consisting of 104 mass units. " | ( Chiriquitoxin, a new tool for mapping ionic channels. Fuhrman, FA; Goldfinger, MD; Kao, CY; Mosher, HS; Yeoh, PN, 1981) | 3.15 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " On isolated frog sartorius muscle fibers, chiriquitoxin is equipotent with tetrodotoxin in blocking the Na+ channel, as shown by their identical dose-response relations on the maximum rate of rise of the action potential." | ( Tetrodotoxin, saxitoxin, chiriquitoxin: new perspectives on ionic channels. Kao, CY, 1981) | 0.83 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (14.29%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (85.71%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||