caprazol profile

caprazol: an antituberculosis antibiotic; isolated from Streptomyces; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	11455930
CHEMBL ID	442922
MeSH ID	M0500476

Synonyms (6)

Synonym
CHEMBL442922
caprazol
MSVZOGHTXZMFOH-XCECKKHWSA-N
(2s,5s,6s)-2-[(s)-[(2s,3r,4s,5r)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy-[(2s,3s,4r,5r)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-6-hydroxy-1,4-dimethyl-3-oxo-1,4-diazepane-5-carboxylic acid
HY-N10499
CS-0572416

Bioassays (1)

Assay ID	Title	Year	Journal	Article
AID382174	Antimicrobial activity against Mycobacterium tuberculosis H37Rv by almar blue assay	2008	Bioorganic & medicinal chemistry, May-01, Volume: 16, Issue:9	Structure-activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (75.00)	29.6817
2010's	2 (25.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 46.33

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	46.33 (24.57)
Research Supply Index	2.20 (2.92)
Research Growth Index	4.32 (4.65)
Search Engine Demand Index	66.09 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (46.33)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (12.50%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (87.50%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
uracil 2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder	3.13	1	pyrimidine nucleobase; pyrimidone	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite
uridine [no description available]	4.53	7	uridines	drug metabolite; fundamental metabolite; human metabolite
3-hydroxybutanal [no description available]	2.1	1
samarium Samarium: An element of the rare earth family of metals. It has the atomic symbol Sm, atomic number 62, and atomic weight 150.36. The oxide is used in the control rods of some nuclear reactors.	3.13	1	f-block element atom; lanthanoid atom
iodine [no description available]	3.13	1	halide anion; monoatomic iodine	human metabolite
sperm motility inhibitor 2 [no description available]	3.13	1
caprazamycin c caprazamycin C: an antituberculosis antibiotic; isolated from Streptomyces; structure in first source	2.43	2
ribose ribopyranose : The pyranose form of ribose.	2.03	1	D-ribose; ribopyranose
caprazamycin b caprazamycin B: anti-tuberculosis lipo-nucleoside antibiotic from Streptomyces sp.; structure in first source	2.43	2

caprazol

Description