caprazol and 3-hydroxybutanal

caprazol has been researched along with 3-hydroxybutanal* in 1 studies

Other Studies

1 other study(ies) available for caprazol and 3-hydroxybutanal

Article	Year
Catalytic asymmetric total synthesis of (+)-caprazol. Organic letters, 2014, Jun-20, Volume: 16, Issue:12 Catalytic asymmetric total synthesis of caprazol, a lipo-nucleoside antibiotic, has been accomplished employing two of the stereoselective C-C bond forming reactions as key transformations. The stereochemistries of the β-hydroxy-α-aminoester moiety at the juncture of the uridine part and diazepanone part, and of the β-hydroxy-α-amino acid moiety embedded in the diazepanone system, were constructed using a diastereoselective isocyanoacetate aldol reaction (dr = 88:12) and an enantioselective anti-nitroaldol reaction catalyzed by a Nd/Na-chiral amide ligand (dr = 12:1, 95% ee), respectively. Topics: Aldehydes; Amino Acids; Anti-Bacterial Agents; Azepines; Catalysis; Molecular Structure; Nucleosides; Stereoisomerism; Uridine	2014

Article

Year

Catalytic asymmetric total synthesis of (+)-caprazol.

Organic letters, 2014, Jun-20, Volume: 16, Issue:12

Catalytic asymmetric total synthesis of caprazol, a lipo-nucleoside antibiotic, has been accomplished employing two of the stereoselective C-C bond forming reactions as key transformations. The stereochemistries of the β-hydroxy-α-aminoester moiety at the juncture of the uridine part and diazepanone part, and of the β-hydroxy-α-amino acid moiety embedded in the diazepanone system, were constructed using a diastereoselective isocyanoacetate aldol reaction (dr = 88:12) and an enantioselective anti-nitroaldol reaction catalyzed by a Nd/Na-chiral amide ligand (dr = 12:1, 95% ee), respectively.

Topics: Aldehydes; Amino Acids; Anti-Bacterial Agents; Azepines; Catalysis; Molecular Structure; Nucleosides; Stereoisomerism; Uridine

2014