Compounds > benz(a)acridine
Page last updated: 2024-12-05

benz(a)acridine

Cross-References

ID SourceID
PubMed CID9180
CHEBI ID82397
SCHEMBL ID297515
MeSH IDM0102335

Synonyms (28)

Synonym
benzo(a)acridine
benz[a]acridine
einecs 205-929-7
7-azabenz(a)anthracene
benz(a)acridine
1,2-benzacridine
ccris 2466
brn 0009262
benzo[a]acridine
d4q8mr98lu ,
unii-d4q8mr98lu
225-11-6
C19337
AKOS024319582
12041-95-1
benzacridine
FT-0631878
85495-86-9
SCHEMBL297515
benz(a)acridine [iarc]
CHEBI:82397
JEGZRTMZYUDVBF-UHFFFAOYSA-N
DTXSID9075371
benz[a]acridine, bcr(r) certified reference material
debenzolyation
Q27155920
1,2-benzacridin
benz (a) acridine (purity)

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Dose-response relationships were obtained for DBa,hAC as well as for BaP."( Experimental studies on the carcinogenicity of five nitrogen containing polycyclic aromatic compounds directly injected into rat lungs.
Brune, H; Deutsch-Wenzel, RP; Grimmer, G, 1983)		0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
organonitrogen heterocyclic compoundAny organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
polycyclic heteroarene
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19908 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (7.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (92.31%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzo(a)pyrene
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.. benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.		2.3720ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
phenobarbital
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.		1.9610barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
benz(a)anthracene
benz(a)anthracene: 4 fused rings of which one is angular in contrast to the linear NAPHTHACENES. tetraphene : An angular ortho-fused polycyclic arene consisting of four fused benzene rings.		1.9710ortho-fused polycyclic arene;
tetraphenes
dibenzacridine
dibenzacridine: RN given refers to dibenz(a,j)acridine		1.9610
benz(c)acridine
[no description available]		8.2260organonitrogen heterocyclic compound;
polycyclic heteroarene
acridines
Acridines: Compounds that include the structure of acridine.. acridine : A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.		3.67100acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole
2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole: structure		1.9710imidazopyridine
chlorogenic acid
caffeoylquinic acid: Antiviral Agent; structure in first source. chlorogenate : A monocarboxylic acid anion that is the conjugate base of chlorogenic acid; major species at pH 7.3.		2.1510cinnamate ester;
tannin		food component;
plant metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Adenocarcinoma, Basal Cell
[description not available]		01.9610
Carcinoma, Epidermoid
[description not available]		01.9610
Cancer of Lung
[description not available]		01.9610
EHS Tumor
[description not available]		01.9610
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.		01.9610
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)		01.9610
Lung Neoplasms
Tumors or cancer of the LUNG.		01.9610
Experimental Neoplasms
[description not available]		01.9610
Cancer of Skin
[description not available]		01.9610
Skin Neoplasms
Tumors or cancer of the SKIN.		01.9610
Experimental Hepatoma
[description not available]		01.9610
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