Page last updated: 2024-12-07

allixin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Allixin is a natural product with potential therapeutic applications. It is extracted from garlic and has been shown to possess various biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Allixin's potential benefits have led to research on its synthesis and pharmacological effects. The compound's unique structure and biological activities make it a promising candidate for the development of new drugs.'

allixin: phytoalexin produced by garlic; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID86374
CHEBI ID172466
SCHEMBL ID1229111
MeSH IDM0192462

Synonyms (19)

Synonym
5-hydroxy-3-methoxy-2-methyl-6-pentylpyran-4-one
125263-70-9
CHEBI:172466
allixin
LS-127455 ,
3-hydroxy-5-methoxy-6-methyl-2-pentyl-4h-pyran-4-one
4h-pyran-4-one, 3-hydroxy-5-methoxy-6-methyl-2-pentyl-
inchi=1/c12h18o4/c1-4-5-6-7-9-10(13)11(14)12(15-3)8(2)16-9/h13h,4-7h2,1-3h
unii-851a356opf
851a356opf ,
SCHEMBL1229111
DTXSID00154719
3-hydroxy-5-methoxy-6-methyl-2-pentyl-4h-pyran-4-one, 9ci
Q4732945
3-hydroxy-5-methoxy-6-methyl-2-pentyl-pyran-4-one
3-hydroxy-6-methyl-5-methoxy-2-pentyl-4h-pyran-4-one
A934068
EX-A5173
STARBLD0002421

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
"The pharmacokinetic behavior of allixin (3-hydroxy-5-methoxy-6-methyl-2-penthyl-4H-pyran-4-one) was investigated in an experimental animal, mice."( Pharmacokinetic study of allixin, a phytoalexin produced by garlic.
Ichikawa, M; Ide, N; Kashimoto, N; Kodera, Y; Ono, K; Sumioka, I; Uda, N; Yoshida, J, 2002
)
0.9

Bioavailability

ExcerptReferenceRelevance
" Most of the administered allixin disappeared within 2 h, and the bioavailability of allixin was estimated to be 31% by obtained area under the blood concentration-time curve (AUC)."( Pharmacokinetic study of allixin, a phytoalexin produced by garlic.
Ichikawa, M; Ide, N; Kashimoto, N; Kodera, Y; Ono, K; Sumioka, I; Uda, N; Yoshida, J, 2002
)
0.92
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
pyranoneAny of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's6 (60.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.87

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.87 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index3.00 (0.95)

This Compound (19.87)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]