Page last updated: 2024-12-07
allixin
Description
Allixin is a natural product with potential therapeutic applications. It is extracted from garlic and has been shown to possess various biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Allixin's potential benefits have led to research on its synthesis and pharmacological effects. The compound's unique structure and biological activities make it a promising candidate for the development of new drugs.'
allixin: phytoalexin produced by garlic; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 86374 |
| CHEBI ID | 172466 |
| SCHEMBL ID | 1229111 |
| MeSH ID | M0192462 |
Synonyms (19)
| Synonym |
|---|
| 5-hydroxy-3-methoxy-2-methyl-6-pentylpyran-4-one |
| 125263-70-9 |
| CHEBI:172466 |
| allixin |
| LS-127455 , |
| 3-hydroxy-5-methoxy-6-methyl-2-pentyl-4h-pyran-4-one |
| 4h-pyran-4-one, 3-hydroxy-5-methoxy-6-methyl-2-pentyl- |
| inchi=1/c12h18o4/c1-4-5-6-7-9-10(13)11(14)12(15-3)8(2)16-9/h13h,4-7h2,1-3h |
| unii-851a356opf |
| 851a356opf , |
| SCHEMBL1229111 |
| DTXSID00154719 |
| 3-hydroxy-5-methoxy-6-methyl-2-pentyl-4h-pyran-4-one, 9ci |
| Q4732945 |
| 3-hydroxy-5-methoxy-6-methyl-2-pentyl-pyran-4-one |
| 3-hydroxy-6-methyl-5-methoxy-2-pentyl-4h-pyran-4-one |
| A934068 |
| EX-A5173 |
| STARBLD0002421 |
Research Excerpts
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|
| "The pharmacokinetic behavior of allixin (3-hydroxy-5-methoxy-6-methyl-2-penthyl-4H-pyran-4-one) was investigated in an experimental animal, mice." | ( Pharmacokinetic study of allixin, a phytoalexin produced by garlic.
Ichikawa, M; Ide, N; Kashimoto, N; Kodera, Y; Ono, K; Sumioka, I; Uda, N; Yoshida, J, 2002) | 0.9 |
Bioavailability
| Excerpt | Reference | Relevance |
|---|
| " Most of the administered allixin disappeared within 2 h, and the bioavailability of allixin was estimated to be 31% by obtained area under the blood concentration-time curve (AUC)." | ( Pharmacokinetic study of allixin, a phytoalexin produced by garlic.
Ichikawa, M; Ide, N; Kashimoto, N; Kodera, Y; Ono, K; Sumioka, I; Uda, N; Yoshida, J, 2002) | 0.92 |
Drug Classes (1)
| Class | Description |
|---|
| pyranone | Any of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 19.87
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 19.87 (24.57) | | Research Supply Index | 2.48 (2.92) | | Research Growth Index | 4.59 (4.65) | | Search Engine Demand Index | 23.28 (26.88) | | Search Engine Supply Index | 3.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (9.09%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (90.91%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |