Page last updated: 2024-11-06

3-methyl-1-phenyltriazene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID85248
CHEMBL ID121569
SCHEMBL ID9119900
SCHEMBL ID22263150
MeSH IDM0074868

Synonyms (27)

Synonym
1-triazene, 1-methyl-3-phenyl-
3-methyl-1-phenyltriazine
wln: 1mnunr
triazene, 3-methyl-1-phenyl-
nsc-136056
nsc136056
3-methyl-1-phenyltriazene
1-phenyl-3-monomethyltriazene
1-phenyl-3-monomethyl-triazene
16033-21-9
phenylmonomethyltriazene
triazene, 3-monomethyl-1-phenyl-
pmmt
methylphenyltriazene
1-methyl-3-phenyltriazene
triazene, 1-methyl-3-phenyl-
1-phenyl-3-methyltriazine
nsc 136056
CHEMBL121569
SCHEMBL9119900
n-(methyldiazenyl)aniline
AKOS006279617
1-phenyl-3-methyltriazene
1-methyl-3-phenyl-1-triazene
DTXSID50166862
phenyl-mono-methyl-triazen
SCHEMBL22263150

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The close correspondence of the two QSAR leaves essentially no means for the synthesis of more potent, less toxic triazenes."( Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice.
Greenberg, N; Hansch, C; Hatheway, GJ; Quinn, FR, 1978
)
0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID24514In vitro biological stability and half-life was measured in phosphate buffer at a pH of 7.4 at 37 degree Centigrade1984Journal of medicinal chemistry, Mar, Volume: 27, Issue:3
Studies of the mode of action of antitumor triazenes and triazines. 6. 1-Aryl-3-(hydroxymethyl)-3-methyltriazenes: synthesis, chemistry, and antitumor properties.
AID1132822Antitumor activity against mouse L1210 cells allografted in mouse assessed as increase of host lifespan1978Journal of medicinal chemistry, Jun, Volume: 21, Issue:6
Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 1. Quantitative structure-activity relationships vs. L1210 leukemia in mice.
AID1148445Half life of the compound at pH 7.4 at 37 degC in presence of serum1978Journal of medicinal chemistry, Jun, Volume: 21, Issue:6
Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.09

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.09 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.28 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.09)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]