Page last updated: 2024-12-07

1-(4-nitrophenyl)-3,3-dimethyltriazene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1-(4-nitrophenyl)-3,3-dimethyltriazene is a compound that is **not widely known or researched**. It's possible that you might have a slight error in the name or the compound itself is quite obscure.

However, let's break down the components of the name to see if we can make any connections:

* **Triazene:** This is a functional group containing a nitrogen chain with three nitrogen atoms.
* **3,3-dimethyl:** This indicates the presence of two methyl groups (CH3) attached to the third carbon atom in the molecule.
* **1-(4-nitrophenyl):** This suggests a phenyl ring (a six-membered carbon ring) with a nitro group (NO2) attached to the fourth position of the ring, and this entire group is attached to the first position of the triazene.

Given the structure, it's possible that this compound could have some interesting properties:

* **Nitro group:** Nitro groups are electron-withdrawing, which could affect the reactivity of the triazene group.
* **Triazene:** Triazenes are known to be involved in a variety of chemical reactions, including those involving nitrogen transfer.
* **Methyl groups:** Methyl groups are often used to sterically hinder reactions and affect the molecule's properties.

**Why it might be important for research:**

* **Potential medicinal applications:** Triazenes have been investigated as potential anticancer agents, and the presence of the nitro group might enhance its biological activity.
* **Organic synthesis:** The compound could be a useful reagent or starting material in organic synthesis, particularly for the synthesis of other nitrogen-containing compounds.
* **Materials science:** The compound's unique structure might lead to interesting properties when incorporated into materials.

**To confirm the importance of this specific compound, you would need to:**

* **Verify the correct name:** Ensure that the name is accurate and that there isn't a typo.
* **Check scientific databases:** Search for publications or patents related to this compound.
* **Consult with experts:** Reach out to chemists or researchers specializing in triazene chemistry or related fields.

Without further information, it's difficult to definitively state the importance of 1-(4-nitrophenyl)-3,3-dimethyltriazene. However, based on its structure and potential properties, it could be a compound of interest in research.

Cross-References

ID SourceID
PubMed CID81648
CHEMBL ID3251113
MeSH IDM0146927

Synonyms (33)

Synonym
1-(p-nitrophenyl)-3,3-dimethyl-triazen
n-methyl-n-[(e)-(4-nitrophenyl)azo]methanamine
triazene,3,3-dimethyl-1-(p-nitrophenyl)
7227-92-1
1-(p-nitrophenyl)-3,3-dimethyltriazine
3,3-dimethyl-1-(p-nitrophenyl)triazene
1-(p-nitrophenyl)-3,3-dimethyltriazene
1-p-nitrofenyl-3,3-dimethyltriazen
1-(4-nitrophenyl)-3,3-dimethyltriazene
wln: wnr dnunn1&1
1-(p-nitrophenyl)-3,3-dimethyltriazen
nsc408428
triazene,3-dimethyl-1-(p-nitrophenyl)-
1-triazene,3-dimethyl-1-(4-nitrophenyl)-
3,3-dimethyl-1-(4-nitrophenyl)triazene
nsc-408428
1-(p-nitrophenyl)-3,3-dimethyl-triazen [german]
1-triazene, 3,3-dimethyl-1-(4-nitrophenyl)-
nsc 408428
ccris 2076
1-(p-nitrophenyl)-3,3-dimethyl-triazene
1-(4-nitrophenyl)-3,3-dimethyltriazine
triazene, 3,3-dimethyl-1-(p-nitrophenyl)-
1-p-nitrofenyl-3,3-dimethyltriazen [czech]
3,3-dimethyl-p-nitrophenyltriazene
(e)-3,3-dimethyl-1-(4-nitrophenyl)triaz-1-ene
n-methyl-n-[(4-nitrophenyl)diazenyl]methanamine
AKOS006274789
CHEMBL3251113
1-p-nitrophenyl-3,3-dimethyltriazene
3,3-dimethyl-1-p-nitrophenyltriazen
3,3-dimethyl-1-(4-nitrophenyl)triaz-1-ene
DTXSID70879149

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The close correspondence of the two QSAR leaves essentially no means for the synthesis of more potent, less toxic triazenes."( Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice.
Greenberg, N; Hansch, C; Hatheway, GJ; Quinn, FR, 1978
)
0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1132824Toxicity in mouse L1210 cells allografted mouse assessed as mortality up to 5 days1978Journal of medicinal chemistry, Jun, Volume: 21, Issue:6
Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 1. Quantitative structure-activity relationships vs. L1210 leukemia in mice.
AID1148441Toxicity in rat assessed as concentration required for producing T/C of 1401978Journal of medicinal chemistry, Jun, Volume: 21, Issue:6
Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]