cytidine transmembrane transporter activity

Definition

Target type: molecularfunction

Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other. [GOC:go_curators]

Cytidine transmembrane transporter activity is a molecular function associated with proteins that facilitate the movement of cytidine across cellular membranes. Cytidine, a nucleoside composed of cytosine and ribose, plays a crucial role in various cellular processes, including DNA and RNA synthesis, as well as the biosynthesis of essential metabolites. Cytidine transmembrane transporters are integral membrane proteins that utilize a variety of mechanisms to mediate cytidine transport. Some transporters operate through passive diffusion, driven by the concentration gradient of cytidine across the membrane. Others employ active transport mechanisms, requiring energy to move cytidine against its concentration gradient. These active transporters often rely on ATP hydrolysis or the electrochemical gradient of other ions for energy. Cytidine transmembrane transporters are essential for maintaining proper intracellular cytidine levels, ensuring the availability of this crucial nucleoside for vital cellular processes. The activity of these transporters can be influenced by factors such as substrate concentration, membrane potential, and the presence of inhibitors. Dysregulation of cytidine transmembrane transport can have significant implications for cellular function, potentially leading to disruptions in DNA and RNA synthesis, as well as metabolic imbalances. Understanding the molecular mechanisms underlying cytidine transmembrane transport is crucial for developing novel therapeutic strategies targeting conditions associated with dysregulation of cytidine metabolism.'
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Proteins (3)

Compounds (19)