nucleoside transmembrane transporter activity

Definition

Target type: molecularfunction

Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other. [GOC:ai]

Nucleoside transmembrane transporter activity is a molecular function that describes the ability of a protein to move nucleosides across cell membranes. Nucleosides are the building blocks of nucleic acids, DNA and RNA, which are essential for all life forms. The movement of nucleosides across cell membranes is crucial for a variety of cellular processes, including DNA replication, RNA transcription, and protein synthesis. This activity is carried out by a variety of membrane transport proteins, including the equilibrative nucleoside transporter (ENT) family and the concentrative nucleoside transporter (CNT) family. These transporters are highly specific for different nucleosides, and their activity can be regulated by a variety of factors, including substrate concentration, pH, and the presence of inhibitors. The transport of nucleosides is critical for maintaining cellular homeostasis and for responding to changes in the environment. For example, during periods of stress, cells may increase their uptake of nucleosides to support increased DNA and RNA synthesis. Conversely, during periods of low nutrient availability, cells may reduce their uptake of nucleosides to conserve energy.'
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Proteins (6)

Compounds (20)