isoamylase complex

Definition

Target type: cellularcomponent

A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. [GOC:jl, PMID:10333591]

The isoamylase complex is a multi-subunit enzyme found in the cytoplasm of eukaryotic cells. It is responsible for the hydrolysis of alpha-1,6-glucosidic linkages in starch and glycogen, a process known as debranching. The complex consists of two subunits, a large subunit (AMY1) and a small subunit (AMY2). The AMY1 subunit contains the catalytic site responsible for the hydrolytic activity, while the AMY2 subunit is believed to be involved in substrate binding and stabilization. The complex is thought to be a dimer of AMY1 and AMY2 subunits, with the AMY1 subunit forming the catalytic core and the AMY2 subunit providing structural support and mediating interactions with other proteins. The isoamylase complex is a vital component of the cellular machinery responsible for the breakdown of starch and glycogen, providing energy for cellular processes.'
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Proteins (1)

Compounds (11)