Page last updated: 2024-10-06

RAS processing

Proteins (12)

ProteinSynonymsTaxonomy
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaEC 2.5.1.58; EC 2.5.1.59; CAAX farnesyltransferase subunit alpha; FTase-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha; GGTase-I-alphaHomo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Bcl-2-like protein 1Bcl2-L-1; Apoptosis regulator Bcl-XHomo sapiens (human)
Protein-S-isoprenylcysteine O-methyltransferaseEC 2.1.1.100; Isoprenylcysteine carboxylmethyltransferase; Prenylated protein carboxyl methyltransferase; PPMT; Prenylcysteine carboxyl methyltransferase; pcCMTHomo sapiens (human)
Protein farnesyltransferase subunit betaFTase-beta; EC 2.5.1.58; CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit betaHomo sapiens (human)
ADP-ribosylation factor-like protein 2Homo sapiens (human)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaGMP-PDE delta; Protein p17Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 17USP17; EC 3.4.19.12; Deubiquitinating enzyme 17-like protein 2; Deubiquitinating protein 3; DUB-3; Ubiquitin carboxyl-terminal hydrolase 17-like protein 2; Ubiquitin thioesterase 17-like protein 2; Ubiquitin-specific-processing protease 17-like protein 2Homo sapiens (human)
CAAX prenyl protease 2EC 3.4.22.-; Farnesylated proteins-converting enzyme 2; FACE-2; Prenyl protein-specific endoprotease 2; RCE1 homolog; hRCE1Homo sapiens (human)
Palmitoyltransferase ZDHHC9EC 2.3.1.225; Zinc finger DHHC domain-containing protein 9; DHHC-9; DHHC9; Zinc finger protein 379; Zinc finger protein 380Homo sapiens (human)
Golgin subfamily A member 7Golgi complex-associated protein of 16 kDaHomo sapiens (human)

Compounds (14)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
cyclic gmpGuanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
cysmethynilan Icmt inhibitor with antineoplastic activity; structure in first source
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Palmitoyl Coenzyme AA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
palmostatin binhibits acyl protein thioesterase 1; structure in first source
fluconazoleTriazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.