Page last updated: 2024-10-06

MTOR signalling

Proteins (30)

ProteinSynonymsTaxonomy
Eukaryotic translation initiation factor 4EeIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding proteinHomo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
RAC-beta serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-betaHomo sapiens (human)
Eukaryotic translation initiation factor 4 gamma 1eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220Homo sapiens (human)
Eukaryotic elongation factor 2 kinaseeEF-2 kinase; eEF-2K; EC 2.7.11.20; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinaseHomo sapiens (human)
Ribosomal protein S6 kinase beta-1S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KAHomo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Eukaryotic translation initiation factor 4BeIF-4BHomo sapiens (human)
Proline-rich AKT1 substrate 140 kDa proline-rich AKT substrateHomo sapiens (human)
Protein phosphatase 1AEC 3.1.3.16; Protein phosphatase 2C isoform alpha; PP2C-alpha; Protein phosphatase IAHomo sapiens (human)
40S ribosomal protein S6Phosphoprotein NP33; Small ribosomal subunit protein eS6Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase FKBP1APPIase FKBP1A; EC 5.2.1.8; 12 kDa FK506-binding protein; 12 kDa FKBP; FKBP-12; Calstabin-1; FK506-binding protein 1A; FKBP-1A; Immunophilin FKBP12; RotamaseHomo sapiens (human)
Serine/threonine-protein kinase STK11EC 2.7.11.1; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19Homo sapiens (human)
Regulatory-associated protein of mTORRaptor; p150 target of rapamycin (TOR)-scaffold proteinHomo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Eukaryotic translation initiation factor 4E-binding protein 14E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-IHomo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Ragulator complex protein LAMTOR5Hepatitis B virus X-interacting protein; HBV X-interacting protein; HBX-interacting protein; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5Homo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
Ragulator complex protein LAMTOR4Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4Homo sapiens (human)
Ras-related GTP-binding protein BRag B; RagB; EC 3.6.5.-Homo sapiens (human)
Ragulator complex protein LAMTOR1Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1; Lipid raft adaptor protein p18; Protein associated with DRMs and endosomes; p27Kip1-releasing factor from RhoA; p27RF-RhoHomo sapiens (human)
Ras-related GTP-binding protein ARag A; RagA; EC 3.6.5.-; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1Homo sapiens (human)
Sodium-coupled neutral amino acid transporter 9Solute carrier family 38 member 9; Up-regulated in lung cancer 11Homo sapiens (human)
HamartinTuberous sclerosis 1 proteinHomo sapiens (human)
Ras-related GTP-binding protein CRag C; RagC; EC 3.6.5.-; GTPase-interacting protein 2; TIB929Homo sapiens (human)
Ras-related GTP-binding protein DRag D; RagD; EC 3.6.5.-Homo sapiens (human)
Ragulator complex protein LAMTOR3Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; MEK-binding partner 1; Mp1; Mitogen-activated protein kinase kinase 1-interacting protein 1; Mitogen-activated protein kinase scaffold protein 1Homo sapiens (human)
Ragulator complex protein LAMTOR2Endosomal adaptor protein p14; Late endosomal/lysosomal Mp1-interacting protein; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; Mitogen-activated protein-binding protein-interacting protein; MAPBP-interacting protein; Roadblock domain-conHomo sapiens (human)

Compounds (8)

CompoundDescription
ArginineAn essential amino acid that is physiologically active in the L-form.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.