sc 51316 and losartan
sc 51316 has been researched along with losartan in 5 studies
Compound Research Comparison
Studies (sc 51316) | Trials (sc 51316) | Recent Studies (post-2010) (sc 51316) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
---|---|---|---|---|---|
9 | 0 | 0 | 7,231 | 1,245 | 2,118 |
Protein Interaction Comparison
Protein | Taxonomy | sc 51316 (IC50) | losartan (IC50) |
---|---|---|---|
Bile salt export pump | Homo sapiens (human) | 9.01 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (80.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Chamberlain, TS; Corpus, VM; Huang, HC; Koepke, JP; McGraw, DE; McMahon, EG; Olins, GM; Palomo, MA; Reitz, DB; Smits, GJ | 1 |
Ashton, WT; Chang, LL; Chang, RS; Chen, TB; Faust, KA; Flanagan, KL; Greenlee, WJ; Lotti, VJ; MacCoss, M; Strelitz, RA | 1 |
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR | 1 |
Blaine, EH; Blehm, DJ; Corpus, VM; Huang, HC; Manning, RE; McMahon, EG; Olins, GM; Palomo, MA; Reitz, DB; Schuh, JR | 1 |
Blaine, EH; Huang, HC; Koepke, JP; Manning, RE; Olins, GM; Reitz, DB; Smits, GJ | 1 |
Reviews
1 review(s) available for sc 51316 and losartan
Article | Year |
---|---|
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan | 2010 |
Other Studies
4 other study(ies) available for sc 51316 and losartan
Article | Year |
---|---|
Synthesis and structure-activity relationships of nonpeptide, potent triazolone-based angiotensin II receptor antagonists.
Topics: Angiotensin Receptor Antagonists; Animals; Binding Sites; Female; Muscle, Smooth; Muscle, Smooth, Vascular; Rabbits; Rats; Structure-Activity Relationship; Tetrazoles; Triazoles; Uterus | 1993 |
Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones.
Topics: Angiotensin II; Animals; Binding Sites; Male; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles | 1993 |
In vitro pharmacology of a nonpeptidic angiotensin II receptor antagonist, SC-51316.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Female; Imidazoles; Kidney; Losartan; Muscle, Smooth, Vascular; Rats; Receptors, Angiotensin; Renin; Tetrazoles; Triazoles; Uterus | 1992 |
In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Enalapril; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tetrazoles; Triazoles | 1993 |