Page last updated: 2024-09-05
raubasine and quinidine
raubasine has been researched along with quinidine in 2 studies
Compound Research Comparison
| Studies (raubasine) | Trials (raubasine) | Recent Studies (post-2010) (raubasine) | Studies (quinidine) | Trials (quinidine) | Recent Studies (post-2010) (quinidine) |
|---|---|---|---|---|---|
| 7 | 0 | 3 | 6,608 | 387 | 594 |
| 140 | 8 | 22 | 6,608 | 387 | 594 |
Protein Interaction Comparison
| Protein | Taxonomy | raubasine (IC50) | quinidine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 6.4 | |
| Cholinesterase | Homo sapiens (human) | 1.23 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 3.32 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 2.8 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3532 | |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | 7.3 | |
| Cholinesterase | Equus caballus (horse) | 7.37 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 6.4 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.7882 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 6.4 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 6.4 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 6.9 | |
| Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | 2.2 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Guengerich, FP; Stöckigt, J; Strobl, GR; von Kruedener, S; Wolff, T | 1 |
| Bianucci, AM; Coi, A; Saraceno, M | 1 |
Other Studies
2 other study(ies) available for raubasine and quinidine
| Article | Year |
|---|---|
Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.
Topics: Alkaloids; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Ethanolamines; Humans; Indoles; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinolines; Secologanin Tryptamine Alkaloids; Yohimbine | 1993 |
Molecular modelling of human CYP2D6 and molecular docking of a series of ajmalicine- and quinidine-like inhibitors.
Topics: Binding Sites; Cross-Linking Reagents; Crystallography, X-Ray; Cytochrome P-450 CYP2D6; Enzyme Inhibitors; Humans; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Quinidine; Secologanin Tryptamine Alkaloids; Thermodynamics | 2008 |