pd 145065 has been researched along with losartan in 3 studies
| Studies (pd 145065) | Trials (pd 145065) | Recent Studies (post-2010) (pd 145065) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
|---|---|---|---|---|---|
| 76 | 1 | 5 | 7,231 | 1,245 | 2,118 |
| Protein | Taxonomy | pd 145065 (IC50) | losartan (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 9.01 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
| Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
| Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calaghan, SC; White, E | 1 |
| Kadekaro, M; Salas, N; Summy-Long, JY; Terrell, ML | 1 |
| Castro-Chaves, P; Leite-Moreira, AF; Roncon-Albuquerque, R | 1 |
3 other study(ies) available for pd 145065 and losartan
| Article | Year |
|---|---|
Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle.
Topics: Angiotensin II; Animals; Endothelin-1; Endothelium; Female; Ferrets; Kinetics; Losartan; Male; Muscle Spindles; Myocardial Contraction; Octoxynol; Oligopeptides; Papillary Muscles; Peptides, Cyclic; Saralasin | 2001 |
Role of prostaglandin, endothelin and sympathetic nervous system on the L-NAME-induced pressor responses in spontaneously hypertensive rats.
Topics: Acetamides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chlorisondamine; Cyclooxygenase Inhibitors; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Indomethacin; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oligopeptides; Prostaglandins; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 2003 |
Endothelin ETA receptors and endothelium partially mediate the positive inotropic and lusitropic effects of angiotensin II.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Endothelium; Losartan; Muscle Contraction; Muscles; Myocardial Contraction; Myocardium; Oligopeptides; Rabbits; Receptor, Endothelin A; Receptors, Endothelin | 2006 |