Compounds > ml-3000
Page last updated: 2024-09-04

ml-3000 and tofacitinib

ml-3000 has been researched along with tofacitinib in 2 studies

Compound Research Comparison

Studies
(ml-3000)		Trials
(ml-3000)		Recent Studies (post-2010)
(ml-3000)		Studies
(tofacitinib)		Trials
(tofacitinib)		Recent Studies (post-2010) (tofacitinib)
1309561,6192141,519

Protein Interaction Comparison

ProteinTaxonomyml-3000 (IC50)tofacitinib (IC50)
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinase JAK2Homo sapiens (human)0.0117
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)0.0815
Tyrosine-protein kinase JAK2Homo sapiens (human)0.2065
Rho-associated protein kinase 2Homo sapiens (human)3.4
Epidermal growth factor receptorHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0815
Tyrosine-protein kinase LckHomo sapiens (human)2.6933
Cytochrome P450 3A4Homo sapiens (human)0.015
Cytochrome P450 2C8Homo sapiens (human)0.0014
Cytochrome P450 2D6Homo sapiens (human)0.0037
Cytochrome P450 2A6Homo sapiens (human)0.012
Tyrosine-protein kinase JAK1Homo sapiens (human)0.0575
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.1411
Cytochrome P450 2C19Homo sapiens (human)0.0016
Tyrosine-protein kinase TecHomo sapiens (human)0.0815
Tyrosine-protein kinase TXKHomo sapiens (human)0.0815
Tyrosine-protein kinase BlkHomo sapiens (human)0.0815
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.0815
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0408
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0006
Tyrosine-protein kinase BTKHomo sapiens (human)0.0815
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.0815
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.0143
Tyrosine-protein kinase JAK3Mus musculus (house mouse)0.664
Tyrosine-protein kinase JAK2Rattus norvegicus (Norway rat)3.57
Tyrosine-protein kinase JAK3Rattus norvegicus (Norway rat)1.2
Serine/threonine-protein kinase TBK1Homo sapiens (human)5.76

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Hampton, T1

Other Studies

2 other study(ies) available for ml-3000 and tofacitinib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Arthritis clinical trial results revealed.
    JAMA, 2007, Jan-03, Volume: 297, Issue:1

    Topics: Acetates; Antirheumatic Agents; Arthritis, Rheumatoid; Chondroitin Sulfates; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Osteoarthritis; Piperidines; Pyrimidines; Pyrroles

2007