mk 0663 has been researched along with l 660,711 in 2 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (l 660,711) | Trials (l 660,711) | Recent Studies (post-2010) (l 660,711) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 45 | 0 | 12 |
| Protein | Taxonomy | mk 0663 (IC50) | l 660,711 (IC50) |
|---|---|---|---|
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | 9.3 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 8 | |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | 2.9 | |
| Bile salt export pump | Homo sapiens (human) | 3.515 | |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | 2.9733 | |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | 2.62 | |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | 7 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 6.4 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
2 other study(ies) available for mk 0663 and l 660,711
| Article | Year |
|---|---|
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |