exp3174 has been researched along with lovastatin in 1 studies
Studies (exp3174) | Trials (exp3174) | Recent Studies (post-2010) (exp3174) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
---|---|---|---|---|---|
236 | 29 | 43 | 4,828 | 698 | 873 |
Protein | Taxonomy | exp3174 (IC50) | lovastatin (IC50) |
---|---|---|---|
Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
Integrin beta-2 | Homo sapiens (human) | 3.09 | |
Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
Neutrophil elastase | Homo sapiens (human) | 0.027 | |
Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
Integrin alpha-L | Homo sapiens (human) | 3.09 | |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Choi, DH; Choi, JS; Yang, SH | 1 |
1 other study(ies) available for exp3174 and lovastatin
Article | Year |
---|---|
Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.
Topics: Acyl Coenzyme A; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Injections, Intravenous; Losartan; Lovastatin; Male; Rats; Rats, Sprague-Dawley; Rhodamine 123; Simvastatin; Tetrazoles; Time Factors | 2011 |