biotin and sirolimus
biotin has been researched along with sirolimus in 4 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 20,711 | 2,368 | 11,516 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | sirolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gibbs, AC | 1 |
| Chen, Z; Fang, Q; He, L; Liu, L; Liu, Z; Xu, Y; Zeng, C | 1 |
| James, C; Kehlenbach, RH; Lenz, C | 1 |
Reviews
1 review(s) available for biotin and sirolimus
| Article | Year |
|---|---|
Elements and modulation of functional dynamics.
Topics: Drug Design; Drug Resistance; Entropy; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Mutation; Protein Conformation; Proteins; Structure-Activity Relationship; Thermodynamics | 2014 |
Other Studies
3 other study(ies) available for biotin and sirolimus
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Dynorphin/KOR inhibits neuronal autophagy by activating mTOR signaling pathway to prevent acute seizure epilepsy.
Topics: Animals; Anticonvulsants; Apoptosis; Autophagy; Biotin; Dynorphins; Epilepsy; Green Fluorescent Proteins; Mammals; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2022 |
RAPIDS, a method for sub-compartmental identification of protein interactomes.
Topics: Ascorbate Peroxidases; Biotin; Biotinylation; Hydrogen Peroxide; Phenols; Sirolimus; Tacrolimus Binding Protein 1A | 2022 |