biotin and nimodipine
biotin has been researched along with nimodipine in 4 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (nimodipine) | Trials (nimodipine) | Recent Studies (post-2010) (nimodipine) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 2,936 | 317 | 597 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | nimodipine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | 0.11 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.19 | |
| Cannabinoid receptor 1 | Homo sapiens (human) | 1.736 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 3.38 | |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Homo sapiens (human) | 0.0298 | |
| Voltage-dependent L-type calcium channel subunit beta-2 | Homo sapiens (human) | 0.0298 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | 7.15 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 0.0699 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | 1.243 | |
| Bile acid receptor | Homo sapiens (human) | 8.96 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Childs, GV; Unabia, G | 1 |
Other Studies
4 other study(ies) available for biotin and nimodipine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Activation of protein kinase C and L calcium channels enhances binding of biotinylated corticotropin-releasing hormone by anterior pituitary corticotropes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Angiotensin II; Animals; Arginine Vasopressin; Biotin; Calcium Channels; Corticotropin-Releasing Hormone; Enzyme Activation; Male; Nimodipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Spectrophotometry; Tetradecanoylphorbol Acetate | 1989 |