bh 3 has been researched along with abt-737 in 4 studies
| Studies (bh 3) | Trials (bh 3) | Recent Studies (post-2010) (bh 3) | Studies (abt-737) | Trials (abt-737) | Recent Studies (post-2010) (abt-737) |
|---|---|---|---|---|---|
| 9 | 0 | 3 | 632 | 0 | 484 |
| Protein | Taxonomy | bh 3 (IC50) | abt-737 (IC50) |
|---|---|---|---|
| Bcl-2-like protein 11 | Homo sapiens (human) | 0.002 | |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | 0.0206 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.02 | |
| BH3-interacting domain death agonist | Homo sapiens (human) | 0.0485 | |
| Apoptosis regulator BAX | Homo sapiens (human) | 0.023 | |
| Bcl-2-like protein 1 | Homo sapiens (human) | 0.0207 | |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | 0.0248 | |
| Aspartyl/asparaginyl beta-hydroxylase | Homo sapiens (human) | 3.44 | |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | 0.0335 | |
| Bcl-2-like protein 2 | Homo sapiens (human) | 0.0335 | |
| Bcl-2-binding component 3, isoforms 1/2 | Homo sapiens (human) | 0.0003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biesterfeld, S; Hoffarth, S; Huber, C; Kröll, M; Schuler, M; Wesarg, E; Wiewrodt, R | 1 |
| Cummings, J; Dive, C; Elmore, S; Foster, K; Greaves, M; Micha, D; Rosenberg, S; Shoemaker, A; Simpson, K; Ward, T | 1 |
| Antonietti, P; Bartsch, G; Blaheta, R; Haferkamp, A; Kögel, D; Mani, J; Rakel, S | 1 |
| Auer, F; Bis, AM; Borkhardt, A; Dujovny, T; Fischer, U; Ginzel, S; Gombert, M; Harlev, D; Keller, B; Koren, A; Levin, C; Miskin, H; Nabhani, S; Postovsky, S; Schipp, C; Stepensky, P; Warnatz, K | 1 |
4 other study(ies) available for bh 3 and abt-737
| Article | Year |
|---|---|
Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Biphenyl Compounds; Butylated Hydroxytoluene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis; Etoposide; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitrophenols; Paclitaxel; Permeability; Piperazines; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Sulfonamides | 2007 |
Circulating biomarkers of cell death after treatment with the BH-3 mimetic ABT-737 in a preclinical model of small-cell lung cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Biomimetic Materials; Biphenyl Compounds; Butylated Hydroxytoluene; Caspase 3; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Keratin-18; Lung Neoplasms; Mice; Nitrophenols; Piperazines; Small Cell Lung Carcinoma; Sulfonamides; Xenograft Model Antitumor Assays | 2008 |
Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Biphenyl Compounds; Blotting, Western; Butylated Hydroxytoluene; Carcinoma, Transitional Cell; Cell Line, Tumor; DNA, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Urinary Bladder Neoplasms | 2016 |
STAT3 gain-of-function mutations associated with autoimmune lymphoproliferative syndrome like disease deregulate lymphocyte apoptosis and can be targeted by BH3 mimetic compounds.
Topics: Apoptosis; Autoimmune Lymphoproliferative Syndrome; Biphenyl Compounds; Butylated Hydroxytoluene; Case-Control Studies; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Family; Fas Ligand Protein; fas Receptor; Female; Gene Expression Profiling; Germ-Line Mutation; Humans; Immunoblotting; Immunophenotyping; Leukocytes, Mononuclear; Lymphocytes; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; STAT3 Transcription Factor; Sulfonamides; T-Lymphocytes | 2017 |