aq-ra 741 has been researched along with pirenzepine in 15 studies
| Studies (aq-ra 741) | Trials (aq-ra 741) | Recent Studies (post-2010) (aq-ra 741) | Studies (pirenzepine) | Trials (pirenzepine) | Recent Studies (post-2010) (pirenzepine) |
|---|---|---|---|---|---|
| 25 | 0 | 3 | 3,812 | 587 | 140 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (93.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brann, MR; Dörje, F; Lambrecht, G; Mutschler, E; Tacke, R; Wess, J | 1 |
| Bolognesi, ML; Budriesi, R; Canossa, M; Chiarini, A; Melchiorre, C; Minarini, A; Spampinato, S | 1 |
| Bolognesi, ML; Chiarini, A; Melchiorre, C; Minarini, A; Spampinato, S | 1 |
| Hendriks, MG; Pfaffendorf, M; Van Zwieten, PA | 2 |
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Doods, H; Entzeroth, M; Mayer, N | 1 |
| Roffel, AF; ten Berge, RE; Zaagsma, J | 1 |
| Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N | 1 |
| Hamstra, JJ; Roffel, AF; Santing, RE; ten Berge, RE; Zaagsma, J | 1 |
| Birdsall, NJ; Lazareno, S | 1 |
| Baumgold, J; Cohen, VI; De La Cruz, R; Jin, B; Reba, RC; Rzeszotarski, WJ | 1 |
| Bechtel, WD; Doods, HN; Engel, W; Ensinger, HA; Entzeroth, M; Ladinsky, H; Mihm, G; Quirion, R; Rudolf, K; Schiavi, GB | 1 |
| Budriesi, R; Chiarini, A; Melchiorre, C; Minarini, A; Spampinato, S; Tumiatti, V | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
1 review(s) available for aq-ra 741 and pirenzepine
| Article | Year |
|---|---|
Therapeutic potential of CNS-active M2 antagonists: novel structures and pharmacology.
Topics: Animals; Benzodiazepinones; Brain; CHO Cells; Cognition Disorders; Cricetinae; Dibenzazepines; Drug Design; Motor Activity; Parasympatholytics; Piperidines; Pirenzepine; Pyridines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1993 |
14 other study(ies) available for aq-ra 741 and pirenzepine
| Article | Year |
|---|---|
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
Topics: Animals; Cells, Cultured; Cricetinae; Humans; N-Methylscopolamine; Parasympatholytics; Receptors, Muscarinic; Scopolamine Derivatives; Transfection | 1991 |
Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed b
Topics: Animals; Atrial Function; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Drug Design; Female; Guinea Pigs; Heart Atria; Ileum; Male; Molecular Structure; Muscarinic Antagonists; Muscle Contraction; Myocardial Contraction; Myocardium; Polyamines; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Submandibular Gland | 1994 |
Synthesis and biological activity of some methoctramine-related tetraamines bearing a 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-one moiety as antimuscarinics: a second generation of highly selective M2 muscarinic receptor antagonists.
Topics: Animals; Benzodiazepines; Diamines; Guinea Pigs; Molecular Structure; Muscarinic Antagonists; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1993 |
Characterization of the muscarinic receptor subtype mediating vasodilation in the rat perfused mesenteric vascular bed preparation.
Topics: Animals; Atropine; Benzodiazepinones; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Methacholine Chloride; Parasympatholytics; Perfusion; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Vasodilation | 1992 |
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
Cardioselectivity of AQ-RA 741, a novel tricyclic antimuscarinic drug.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cats; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Conditional involvement of muscarinic M1 receptors in vagally mediated contraction of guinea-pig bronchi.
Topics: Adrenergic beta-Antagonists; Animals; Benzodiazepinones; Bronchoconstriction; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Timolol; Vagus Nerve | 1995 |
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture.
Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic | 1994 |
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Benzodiazepinones; Bronchial Hyperreactivity; Diamines; Disease Models, Animal; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Histamine; Hypersensitivity; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1995 |
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Topics: Animals; Atropine; Benzodiazepinones; Endothelium, Vascular; Hypertension; Male; Mesenteric Artery, Superior; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic; Vasodilation | 1993 |
Estimation of competitive antagonist affinity from functional inhibition curves using the Gaddum, Schild and Cheng-Prusoff equations.
Topics: Acetylcholine; Animals; Benzodiazepinones; Binding, Competitive; CHO Cells; Cricetinae; Drug Antagonism; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indicators and Reagents; Membranes; Models, Biological; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Regression Analysis | 1993 |
Synthesis and structure-activity relationship of some 5-[[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro-5H- benzo[b,e][1,4]diazepin-11-ones as M2-selective antimuscarinics.
Topics: Animals; Benzodiazepinones; Brain; Mice; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1993 |
The design of novel methoctramine-related tetraamines as muscarinic receptor subtype selective antagonists.
Topics: Animals; Atrial Function; Benzodiazepines; Benzodiazepinones; Diamines; Drug Design; Guinea Pigs; Heart Atria; Ileum; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Submandibular Gland; Trachea | 1995 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |