spirobrassinin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

spirobrassinin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	188830
CHEMBL ID	4539060
MeSH ID	M0376044

Synonyms (7)

Synonym
113866-40-3
(-)-spirobrassinin
spirobrassinin
(s)-(-)-spirobrassinin
spirobrassinine
DTXSID60904136
CHEMBL4539060

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay ID	Title	Year	Journal	Article
AID1617009	Neuroprotective activity in rat C6 cells assessed as NGF secretion at 20 uM incubated for 24 hrs by ELISA relative to control	2019	Journal of natural products, 11-22, Volume: 82, Issue:11	Thiohydantoin and Hydantoin Derivatives from the Roots of
AID1617010	Cytotoxicity against rat C6 cells assessed as cell viability at 20 uM incubated for 24 hrs by MTT assay relative to control	2019	Journal of natural products, 11-22, Volume: 82, Issue:11	Thiohydantoin and Hydantoin Derivatives from the Roots of
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (63.64)	29.6817
2010's	3 (27.27)	24.3611
2020's	1 (9.09)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (9.09%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (90.91%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
isatin tribulin: endogenous MONOAMINE OXIDASE inhibitory activity extractable into ethyl acetate found in brain and many mammalian tissues and fluids; ISATIN is a major component; produced in excess following alcohol withdrawal;	7.06	1	indoledione	EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
oxazoles Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.	2	1	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
thiazoles [no description available]	4.84	10	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
omega-n-methylarginine omega-N-Methylarginine: A competitive inhibitor of nitric oxide synthetase.. N(omega)-methyl-L-arginine : A L-arginine derivative with a N(omega)-methyl substituent.	2.21	1	amino acid zwitterion; arginine derivative; guanidines; L-arginine derivative; non-proteinogenic L-alpha-amino acid
camalexin camalexin : An indole phytoalexin that is indole substituted at position 3 by a 1,3-thiazol-2-yl group.	3.11	1	1,3-thiazoles; indole phytoalexin	metabolite
glucobrassicin glucobrassicin: isolated from Brussels sprouts; structure given in first source. glucobrassicin : An indolylmethylglucosinolic acid that is 1-thio-beta-D-glucopyranose having a 2-(1H-indol-3-yl)-N-(sulfooxy)ethanimidoyl group attached to the anomeric sulfur.	2.04	1	indolyl carbohydrate; indolylmethylglucosinolic acid
sesquiterpenes [no description available]	4.52	7
brassinin [no description available]	3.53	2	dithiocarbamic ester; indole phytoalexin
shogaol shogaol: from ginger, ZINGIBER OFFICINALE; less mutagenic than GINGEROL; structure given in first source	2.21	1	enone; monomethoxybenzene; phenols
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	2.04	1	chalcogen; nonmetal atom	macronutrient

Condition	Indicated	Relationship Strength	Studies	Trials
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	0	2.93	1	0
Experimental Neoplasms [description not available]	0	2.93	1	0

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