Compounds > serrawettin w2
Page last updated: 2024-11-08

serrawettin w2

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

serrawettin W2: extracellular cyclic lipopeptide which promotes flagellum-dependent & -independent spreading growth of Serratia marcescens; amino acid sequence given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID164436
MeSH IDM0198718

Synonyms (6)

Synonym
serrawettin w2
140909-80-4
(3s,6r,12s,15r)-6-benzyl-3-[(2s)-butan-2-yl]-19-heptyl-9-[(1r)-1-hydroxyethyl]-12-(hydroxymethyl)-15-(2-methylpropyl)-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
l-isoleucine, n-(n-(n-(n-(n-(3-hydroxy-1-oxodecyl)-d-leucyl)-l-seryl)-l-threonyl)-d-phenylalanyl)-, rho-lactone
DTXSID10930940
6-benzyl-3-(butan-2-yl)-19-heptyl-5,8,11,14,17-pentahydroxy-9-(1-hydroxyethyl)-12-(hydroxymethyl)-15-(2-methylpropyl)-1-oxa-4,7,10,13,16-pentaazacyclononadeca-4,7,10,13,16-pentaen-2-one

Research Excerpts

Overview

Serrawettin W2 was shown to be a novel cyclodepsipeptide containing a fatty acid (3-hydroxydecanoic acid) and five amino acids.

ExcerptReferenceRelevance
"Serrawettin W2 was shown to be a novel cyclodepsipeptide containing a fatty acid (3-hydroxydecanoic acid) and five amino acids."( A novel extracellular cyclic lipopeptide which promotes flagellum-dependent and -independent spreading growth of Serratia marcescens.
Hara-Hotta, H; Isa, K; Kaneda, K; Matsuyama, T; Nakagawa, Y; Yano, I, 1992)		1
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-butyrolactone
4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.		2.420butan-4-olidemetabolite;
neurotoxin
thiazoles
[no description available]		2.1101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
serratamolide
serratamolide: exhibits cation specificity in biomembrane transport; structure		2.2110
plasminogen activator inhibitor 2
N-butyrylhomoserine lactone: quorum sensing compound biosynthesized by LasI protein; structure given in first source		1.9910N-acyl-amino acid
homoserine lactone
homoserine lactone: a putative signal for starvation in E. coli; structure in first source. homoserinium lactone : The conjugate acid of homoserine lactone; major species at pH 7.3.. homoserine lactone : A butan-4-olide having an amino substituent at the 2-position.		210ammonium ion derivative;
organic cation
n-hexanoyl-l-homoserine lactone
N-hexanoyl-L-homoserine lactone: structure in first source		1.9910N-acyl-amino acid
prodigiosin
Prodigiosin: 4-Methoxy-5-((5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl)- 2,2'-bi-1H-pyrrole. A toxic, bright red tripyrrole pigment from Serratia marcescens and others. It has antibacterial, anticoccidial, antimalarial, and antifungal activities, but is used mainly as a biochemical tool.. prodigiosin : A member of the class of tripyrroles that is a red-coloured pigment with antibiotic properties produced by Serratia marcescens.		2.5720
althiomycin
althiomycin: structure. althiomycin : A peptide antibiotic isolated from soil and enteric bacteria. It is a protein synthesis inhibitor which exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria.		2.1101,3-thiazoles;
aldoxime;
ether;
gamma-lactam;
pentapeptide;
peptide antibiotic;
primary alcohol;
pyrroline;
secondary carboxamide;
tertiary carboxamide		antibacterial agent;
bacterial metabolite;
protein synthesis inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Acute Promyelocytic Leukemia
[description not available]		02.610
Leukemia, Promyelocytic, Acute
An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.		02.610