Compounds > r 29148
Page last updated: 2024-12-06

r 29148

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

R-29148 : A member of the class of oxazolidines that is 1,3-oxazolidine which is substituted by two methyl groups, dichloroacetyl group and a methyl group at positions 2, 3 and 5, respectively. It is a herbicide safener. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID62019
CHEMBL ID2269057
CHEBI ID147358
SCHEMBL ID167473
MeSH IDM0243287

Synonyms (31)

Synonym
3-(dichloroacetyl)-2,2,5-trimethyl-1,3-oxazolidine
52836-31-4
oxazolidine, 3-(dichloroacetyl)-2,2,5-trimethyl-
r 29148
2,2,5-trimethyl-3-dichloroacetyl oxazolidine
2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)ethanone
2,2-dichloro-1-(2,2,5-trimethyl-1,3-oxazolidin-3-yl)ethanone
3-(dichloroacetyl)-2,2,5-trimethyloxazolidine
2,2-dichloro-1-(2,2,5-trimethyloxazolidin-3-yl)ethanone
r29148
2,2,5-trimethyl-3-dichloroacetyl-1,3-oxazolidine
r-29148
2,2,5-trimethyl-3-(dichloroacetyl)oxazolidine
2,2-dichloro-1-(2,2,5-trimethyloxazolidin-3-yl)ethan-1-one
CHEBI:147358
2,2-dichloro-1-(2,2,5-trimethyl-1,3-oxazolidin-3-yl)ethan-1-one
2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine
A829273
jly7k2sjek ,
einecs 258-214-7
unii-jly7k2sjek
ethanone, 2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)-
CHEMBL2269057
AKOS022171993
SCHEMBL167473
YNQSILKYZQZHFJ-UHFFFAOYSA-N
DTXSID5028031
Q27281571
2,2,5-trimethyl-3-dichloroacetyloxazolidine
3-(dichloroacetyl)-2,2,5-trimethyloxazolidine 100 microg/ml in acetonitrile
oxazolidine, 3-(dichloroacetyl)-2,2,5-trimethyl- (9ci); 2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)ethanone; 2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine; 2,2,5-trimethyl-3-(dichloroacetyl)oxazolidine; r 29148
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
herbicide safenerA compound used with herbicides that reduces the effect of the herbicide on crop plants or otherwise improves the selectivity of the herbicide for weed species over the crop plant.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
oxazolidines
tertiary carboxamideA carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2).
organochlorine compoundAn organochlorine compound is a compound containing at least one carbon-chlorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1100793Binding affinity to SafBP receptor in Zea mays (maize) seedlings by [3H]Saf(R-29148) binding assay2000Journal of agricultural and food chemistry, Mar, Volume: 48, Issue:3
Comparative three-dimensional quantitative structure-activity relationship study of safeners and herbicides.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbamates
[no description available]		1.9810amino-acid anion
acetochlor
acetochlor : A monocarboxylic acid amide that is N-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively.		210aromatic amide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
alachlor
alachlor : An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.		210aromatic amide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
metolachlor
metolachlor: structure given in first source. metolachlor : A racemate that consists of equimolar amounts of (R)- and (S)-metolachlor.. 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide : An organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl) group at the nitrogen atom.		210aromatic amide;
benzenes;
ether;
organochlorine compound
propachlor
propachlor: structure. propachlor : An anilide that consists of 2-chloroacetanilide bearing an N-isopropyl substituent.		210anilide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
triallate
Triallate: A pre-emergence, selective herbicide for the control of wild oats in various crops.		210tertiary amine
cdaa
CDAA: structure		210tertiary carboxamide
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		2.9401,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
2,2-dichloroacetamide
[no description available]		1.9810
eptc
EPTC: minor descriptor (72-82); online & Index Medicus search HERBICIDES, CARBAMATE (72-82)		210tertiary amine
pebulate
pebulate: structure		210tertiary amine
cycloate
[no description available]		210primary aliphatic amine
s,n,n'-tripropylthiocarbamate
Reward: An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure.. vernolate : A monounsaturated fatty acid anion that is the conjugate base of vernolic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.		210tertiary amine
molinate
molinate : A member of the class of azepanes that is azepane in which the nitrogen is substituted by an (ethylsulfanyl)carbonyl group, -C(=O)SEt. A thiocarbamate herbicide not approved for use in the U.S. or European Union, it is used control grass weeds in rice paddies.		210azepanes;
monothiocarbamic ester		agrochemical;
antispermatogenic agent;
herbicide
benthiocarb
Saturn: The sixth planet in order from the sun. It is one of the five outer planets of the solar system. Its twelve natural satellites include Phoebe and Titan.		210monochlorobenzenes;
monothiocarbamic ester
dichlormid
dichlormid: antidote for EPTC injury in corn; structure		2.6830tertiary carboxamide
benoxacor
benoxacor: a herbicide safener that protects corn from injury by metachlor		210benzoxazine
s-methyl diethylthiocarbamate
S-methyl diethylthiocarbamate: structure in first source		210
ConditionIndicatedRelationship StrengthStudiesTrials