Page last updated: 2024-12-06
r 29148
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
R-29148 : A member of the class of oxazolidines that is 1,3-oxazolidine which is substituted by two methyl groups, dichloroacetyl group and a methyl group at positions 2, 3 and 5, respectively. It is a herbicide safener. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 62019 |
| CHEMBL ID | 2269057 |
| CHEBI ID | 147358 |
| SCHEMBL ID | 167473 |
| MeSH ID | M0243287 |
Synonyms (31)
| Synonym |
|---|
| 3-(dichloroacetyl)-2,2,5-trimethyl-1,3-oxazolidine |
| 52836-31-4 |
| oxazolidine, 3-(dichloroacetyl)-2,2,5-trimethyl- |
| r 29148 |
| 2,2,5-trimethyl-3-dichloroacetyl oxazolidine |
| 2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)ethanone |
| 2,2-dichloro-1-(2,2,5-trimethyl-1,3-oxazolidin-3-yl)ethanone |
| 3-(dichloroacetyl)-2,2,5-trimethyloxazolidine |
| 2,2-dichloro-1-(2,2,5-trimethyloxazolidin-3-yl)ethanone |
| r29148 |
| 2,2,5-trimethyl-3-dichloroacetyl-1,3-oxazolidine |
| r-29148 |
| 2,2,5-trimethyl-3-(dichloroacetyl)oxazolidine |
| 2,2-dichloro-1-(2,2,5-trimethyloxazolidin-3-yl)ethan-1-one |
| CHEBI:147358 |
| 2,2-dichloro-1-(2,2,5-trimethyl-1,3-oxazolidin-3-yl)ethan-1-one |
| 2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine |
| A829273 |
| jly7k2sjek , |
| einecs 258-214-7 |
| unii-jly7k2sjek |
| ethanone, 2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)- |
| CHEMBL2269057 |
| AKOS022171993 |
| SCHEMBL167473 |
| YNQSILKYZQZHFJ-UHFFFAOYSA-N |
| DTXSID5028031 |
| Q27281571 |
| 2,2,5-trimethyl-3-dichloroacetyloxazolidine |
| 3-(dichloroacetyl)-2,2,5-trimethyloxazolidine 100 microg/ml in acetonitrile |
| oxazolidine, 3-(dichloroacetyl)-2,2,5-trimethyl- (9ci); 2,2-dichloro-1-(2,2,5-trimethyl-3-oxazolidinyl)ethanone; 2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine; 2,2,5-trimethyl-3-(dichloroacetyl)oxazolidine; r 29148 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Roles (1)
| Role | Description |
|---|---|
| herbicide safener | A compound used with herbicides that reduces the effect of the herbicide on crop plants or otherwise improves the selectivity of the herbicide for weed species over the crop plant. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Drug Classes (3)
| Class | Description |
|---|---|
| oxazolidines | |
| tertiary carboxamide | A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2). |
| organochlorine compound | An organochlorine compound is a compound containing at least one carbon-chlorine bond. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Bioassays (1)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1100793 | Binding affinity to SafBP receptor in Zea mays (maize) seedlings by [3H]Saf(R-29148) binding assay | 2000 | Journal of agricultural and food chemistry, Mar, Volume: 48, Issue:3 | Comparative three-dimensional quantitative structure-activity relationship study of safeners and herbicides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.66
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.66) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||