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phoslactomycin b

Description

phoslactomycin B: structure given in first source; isolated from Streptomyces nigrescens SC-273 [MeSH]

Phoslactomycin B : no description available [CHeBI]

Cross-References

ID SourceID
PubMed CID11497184
CHEBI ID80042
MeSH IDM0167943

Synonyms (6)

Synonym
122856-26-2
phoslactomycin b
CHEBI:80042
[(1e,3r,4r,6r,7z,9z)-3-(2-aminoethyl)-10-cyclohexyl-1-[(2s,3s)-3-ethyl-6-oxo-2,3-dihydropyran-2-yl]-3,6-dihydroxydeca-1,7,9-trien-4-yl] dihydrogen phosphate
Q27149191
DTXSID401100396

Drug Classes (1)

ClassDescription
2-pyranonesA pyranone based on the structure of 2H-pyran-2-one and its substituted derivatives.

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (15.38)18.7374
1990's0 (0.00)18.2507
2000's10 (76.92)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (7.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (92.31%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
6-pentylpyrone2-pyranonesmetabolite00low000000
mevastatin2-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)
antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite
00low000000
2-pyrone2-pyranones00low000000
7,8-dihydromethysticin2-pyranones;
aromatic ether
00low000000
7,8-dihydro-5,6-dehydrokawain2-pyranones;
aromatic ether
00low000000
ml 236a2-pyranones;
carbobicyclic compound;
hexahydronaphthalenes;
polyketide;
secondary alcohol
antiatherosclerotic agent;
anticholesteremic drug;
antilipemic drug;
antimicrobial agent;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
fungal metabolite
00low000000
(+-)-Dihydromethysticin2-pyranones;
aromatic ether
00low000000
parasorbic acid2-pyranones00low000000
2,4-dimethyl-6-oxo-N-[(2,4,6-trifluorophenyl)methyl]-3-pyrancarboxamide2-pyranones00low000000
5,6-dehydrokawain2-pyranones;
aromatic ether
00low000000
kavain2-pyranones;
aromatic ether
00low000000
methysticin2-pyranones;
aromatic ether
00low000000
yangonin2-pyranones;
aromatic ether
00low000000
citreoviridin2-pyranones00low000000
fostriecin2-pyranones;
olefinic compound;
phosphate monoester;
polyketide;
primary allylic alcohol;
secondary allylic alcohol;
triol
antineoplastic agent;
apoptosis inhibitor;
bacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
topoisomerase II inhibitor
00low000000
monacolin j2-pyranones;
carbobicyclic compound;
hexahydronaphthalenes;
polyketide;
secondary alcohol
antimicrobial agent;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
fungal metabolite
00low000000
7,8-Dihydroyangonin2-pyranones;
aromatic ether
00low000000
dihydrokavain2-pyranones;
aromatic ether
00low000000
obolactone2-pyranones;
4-pyranones
antineoplastic agent;
plant metabolite
00low000000
dihydromonacolin l2-pyranones;
octahydronaphthalenes
00low000000
monacolin l2-pyranones;
hexahydronaphthalenes;
polyketide;
secondary alcohol
anticholesteremic drug;
Aspergillus metabolite;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
00low000000
kavain2-pyranones;
aromatic ether
00low000000
4-hydroxy-6-methyl-2-pyrone2-pyranones00low000000
hispidin2-pyranones;
catechols
antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite
00low000000
cryptocaryol a2-pyranones;
pentol
plant metabolite00low000000
methysticin2-pyranones;
aromatic ether
00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
quinuclidinesquinuclidines;
saturated organic heterobicyclic parent
2009200915.0low000100
alkenes2009200915.0low000100
caprylatesfatty acid anion 8:0;
straight-chain saturated fatty acid anion
human metabolite;
Saccharomyces cerevisiae metabolite
2007200717.0low000100
phosphazomycin c11989202024.7high020010
phoslactomycin a1989198935.0high020000
fostriecin2-pyranones;
olefinic compound;
phosphate monoester;
polyketide;
primary allylic alcohol;
secondary allylic alcohol;
triol
antineoplastic agent;
apoptosis inhibitor;
bacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
topoisomerase II inhibitor
2009200915.0medium000100
chiniofon2009200915.0low000100
beta-isocupreidine2009200915.0high000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020