| Assay ID | Title | Year | Journal | Article |
|---|
| AID51935 | Functional potency was determined by concentration required for activation of OX1 (Orexin-1) receptor expressed in chinese hamster ovary cells (CHO) and increasing the intracellular calcium concentration | 2001 | Bioorganic & medicinal chemistry letters, Mar-12, Volume: 11, Issue:5
| Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. |
| AID767534 | Agonist activity at OX2 receptor (unknown origin) expressed in RD-HGA16 cells assessed as calcium mobilization by fluorescence assay | 2013 | Journal of medicinal chemistry, Sep-12, Volume: 56, Issue:17
| Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. |
| AID1062205 | Agonist activity at human OX2 receptor overexpressed in CHO-RD-HGA16 cells assessed as calcium mobilization after 15 mins by fluorescence assay | 2013 | ACS medicinal chemistry letters, Dec-12, Volume: 4, Issue:12
| Truncated Orexin Peptides: Structure-Activity Relationship Studies. |
| AID1062207 | Agonist activity at human OX1 receptor overexpressed in CHO-RD-HGA16 cells assessed as calcium mobilization after 15 mins by fluorescence assay | 2013 | ACS medicinal chemistry letters, Dec-12, Volume: 4, Issue:12
| Truncated Orexin Peptides: Structure-Activity Relationship Studies. |
| AID767535 | Agonist activity at OX1 receptor (unknown origin) expressed in RD-HGA16 cells assessed as calcium mobilization by fluorescence assay | 2013 | Journal of medicinal chemistry, Sep-12, Volume: 56, Issue:17
| Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. |
| AID1062203 | Selectivity ratio of EC50 for human OX2 receptor to EC50 for human OX1 receptor | 2013 | ACS medicinal chemistry letters, Dec-12, Volume: 4, Issue:12
| Truncated Orexin Peptides: Structure-Activity Relationship Studies. |
| AID1878175 | Selectivity index, ratio of EC50 for agonist activity at OX1R (unknown origin) to EC50 for agonist activity at OX2R (unknown origin) | | | |
| AID1878169 | Agonist activity at OX1R (unknown origin) | | | |
| AID150548 | Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometry | 2001 | Bioorganic & medicinal chemistry letters, Mar-12, Volume: 11, Issue:5
| Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. |
| AID1249695 | Induction of wakefullness in C57BL/6J mouse assessed as increase in wake time by measuring EEG/EMG signals at 3 nmol, icv dosed on every other day during light phase | 2015 | Journal of medicinal chemistry, Oct-22, Volume: 58, Issue:20
| Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists. |
| AID1878172 | Agonist activity at OX2R (unknown origin) | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |