diazalo: noncarcinogenic cpd involved in transnitrosating activity in rats & human gastric juice [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 6628 |
| CHEMBL ID | 1606452 |
| CHEBI ID | 143725 |
| SCHEMBL ID | 105447 |
| MeSH ID | M0377082 |
| Synonym |
|---|
| nsc-5290 |
| nsc5290 |
| benzenesulfonamide, n,4-dimethyl-n-nitroso- |
| toluene-p-sulfonylmethylnitrosamide |
| p-tolylsulfonyl-methyl-nitrosamid |
| n-nitroso-n-methyl-p-toluenesulfamide |
| p-tolylsulfonylmethylnitrosamide |
| nsc313 |
| methylnitroso-p-toluenesulfonamide |
| wln: onn1&swr d1 |
| n-nitroso-n-methyl-4-tolylsulfonamide |
| diazale |
| nsc-313 |
| benzenesulfonamide,4-dimethyl-n-nitroso- |
| n-methyl-n-nitroso-p-tolylsulfonylamide |
| 80-11-5 |
| p-toluenesulfonamide, n-methyl-n-nitroso- |
| n-methyl-n-nitroso-p-toluenesulfonamide |
| p-tolylsulfonylmethylnitrosamine |
| diazald |
| diazald(r), 99% |
| brn 2214345 |
| n-methyl-n-nitrosotoluene-4-sulphonamide |
| einecs 201-252-6 |
| nsc 313 |
| p-tolylsulfonyl-methyl-nitrosamid [german] |
| diazalo |
| ai3-52479 |
| hsdb 5234 |
| MLS001361349 |
| smr000875348 |
| n,4-dimethyl-n-nitrosobenzenesulfonamide |
| CHEBI:143725 |
| n,4-dimethyl-n-nitroso-benzenesulfonamide |
| A839839 |
| NCGC00247025-01 |
| AKOS005720984 |
| T0323 |
| p-toluenesulfonyl-n-methyl-n-nitrosamide |
| HMS2230C22 |
| STL146734 |
| 4-11-00-00478 (beilstein handbook reference) |
| unii-k3089966la |
| n-nitroso-n-methyl-4-toluenesulfonamide |
| k3089966la , |
| FT-0631355 |
| AB00201 |
| p-tolylsulfonylmethylnitrosamide [mi] |
| p-tolylsulfonylmethylnitrosamide [hsdb] |
| methyl-n-nitroso-p-toluenesulfonamide, n- |
| 102832-11-1 |
| HMS3369J17 |
| n-methyl-n-nitrosotoluene-p-sulphonamide |
| n-methyl-n-nitroso-p-toluenesul-fonamide |
| n-methyl n-nitroso-p-toluenesulfonamide |
| n-methyl-n-nitroso-p-toluene sulfonamide |
| n-methyl-n-nitroso-4-toluenesulfonamide |
| n-methyl-n-nitroso-p-toluenesulphonamide |
| SCHEMBL105447 |
| DTXSID8058827 |
| W-104248 |
| CHEMBL1606452 |
| n-nitroso-n-methyl-p-toluenesulfonamide |
| n-methyl-n-nitrosotoluene-4-sulfonamide |
| p-tolylsulfonylmethylnitrosoamide |
| n-methyl-n-nitroso, p-toluene sulfonamide |
| n,4-dimethyl-n'-oxobenzenesulfonohydrazide # |
| diazogen |
| n-methyl-n-nitroso-p-toluenesulfonamide, purum, >=98.0% (hplc) |
| n,4-dimethyl-n'-oxobenzene-1-sulfonohydrazide |
| AS-64766 |
| n-methyl-n-nitrosotoluene-4-sulphonamide (ntols) |
| Q20650189 |
| AMY41341 |
| n-methyl-n-nitroso-p-toluensulfonamide |
| diazald(r)-n-methyl-13c |
| Class | Description |
|---|---|
| sulfonamide | An amide of a sulfonic acid RS(=O)2NR'2. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 23.9341 | 0.0072 | 15.7588 | 89.3584 | AID588342 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 50.1187 | 0.1000 | 22.9075 | 100.0000 | AID485364 |
| 67.9K protein | Vaccinia virus | Potency | 28.1838 | 0.0001 | 8.4406 | 100.0000 | AID720580 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 63.0957 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 6.5131 | 0.0041 | 9.9848 | 25.9290 | AID504444 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.59) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (11.11%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||