Motival: combination of fluphenazine & nortriptyline [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 6455338 |
| MeSH ID | M0090670 |
| Synonym |
|---|
| motipress |
| 66555-51-9 |
| motival |
| 1-piperazineethanol, 4-(3-(2-(trifluoromethyl)-10h-phenothiazin-10-yl)propyl)-, dihydrochloride, mixt. with 3-(10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5-ylidene)-n-methyl-1-propanamine hydrochloride |
| DTXSID10216731 |
| n-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;trihydrochloride |
| xqiumqdlobbwjm-uhfffaoysa-n |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (50.00%) | 5.53% |
| Reviews | 1 (16.67%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 2 (33.33%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| fluphenazine | N-alkylpiperazine; organofluorine compound; phenothiazines | anticoronaviral agent; dopaminergic antagonist; phenothiazine antipsychotic drug | 1981 | 1984 | 41.5 | high | 3 | 4 | 0 | 0 | 0 | 0 | |
| nomifensine | isoquinolines | dopamine uptake inhibitor | 1983 | 1983 | 41.0 | medium | 1 | 1 | 0 | 0 | 0 | 0 | |
| nortriptyline | organic tricyclic compound; secondary amine | adrenergic uptake inhibitor; analgesic; antidepressant; antineoplastic agent; apoptosis inducer; drug metabolite | 1981 | 1984 | 41.5 | high | 3 | 4 | 0 | 0 | 0 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anxiety Disorders | 0 | 1983 | 1983 | 41.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Anxiety Neuroses | 0 | 1983 | 1983 | 41.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Bladder Diseases | 0 | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Colonic Diseases, Functional | 0 | 1981 | 1982 | 42.5 | medium | 1 | 2 | 0 | 0 | 0 | 0 | |
| Depression, Endogenous | 0 | 1983 | 1983 | 41.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Depressive Disorder | 0 | 1983 | 1983 | 41.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Neuroses | 0 | 1982 | 1982 | 42.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Neurotic Disorders | 0 | 1982 | 1982 | 42.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Symptom Cluster | 0 | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Syndrome | 0 | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 | |
| Urination Disorders | 0 | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |