Compounds > mollisin
Page last updated: 2024-12-07

mollisin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

mollisin: halometabolite of Mollisia caesia; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID99583
CHEMBL ID5193158
MeSH IDM0056209

Synonyms (14)

Synonym
nsc244389
mollisin
1, 8-(dichloroacetyl)-5-hydroxy-2,7-dimethyl-
nsc-244389
667-92-5
1,4-naphthoquinone, 8-(dichloroacetyl)-5-hydroxy-2,7-dimethyl-
1,4-naphthalenedione, 8-(dichloroacetyl)-5-hydroxy-2,7-dimethyl-
nsc 244389
DTXSID80216849
CHEMBL5193158
n,n-bis (2-hydroxyethyl)tridecylamine
mollisine
10.14272/LBLPBDUCKUHMIA-UHFFFAOYSA-N.1
doi:10.14272/lblpbduckuhmia-uhfffaoysa-n.1
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID1869323Antiproliferative activity against human MCF7 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869322Antiproliferative activity against human HCT-116 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869328Antiproliferative activity against human CAL-51 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869327Antiproliferative activity against human BT-549 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869321Antiproliferative activity against human HCC1954 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869324Antiproliferative activity against human MOLM-13 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869325Antiproliferative activity against human MV4-11 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
AID1869326Antiproliferative activity against human K562 cells measured after 72 hrs by SRB assay2022Journal of natural products, 06-24, Volume: 85, Issue:6
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
juglone
juglone: structure. juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.		3.5110hydroxy-1,4-naphthoquinonegeroprotector;
herbicide;
reactive oxygen species generator
beta-lapachone
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase. beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.		3.5110benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite
naphthazarin
naphthazarin: fish toxin; isolated for first time from the walnut onigurmi, Juglans mandshurica maxim var. Sieboldiana Makino; structure. naphthazarin : A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.		3.5110hydroxy-1,4-naphthoquinoneacaricide;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
geroprotector;
plant metabolite
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.		2.8840
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		03.3310
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		03.3310