Compounds > dihydrocarvone
Page last updated: 2024-11-05

dihydrocarvone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Dihydrocarvone is a bicyclic monoterpene ketone that exists in two enantiomeric forms: (-)-dihydrocarvone and (+)-dihydrocarvone. It is a colorless liquid with a characteristic camphoraceous odor. Dihydrocarvone is a common constituent of essential oils derived from plants such as caraway, dill, and spearmint. It can be synthesized through the catalytic hydrogenation of carvone, a naturally occurring monoterpene ketone. Dihydrocarvone exhibits various biological activities, including anti-inflammatory, antimicrobial, and antioxidant effects. It has also been found to possess insecticidal properties and is used in the formulation of insect repellents. The study of dihydrocarvone is of interest due to its potential applications in various industries, including pharmaceuticals, cosmetics, and food additives. Its unique chemical structure and biological activities make it a promising candidate for the development of new therapeutic agents and bioactive compounds.'

dihydrocarvone: found in caraway oil; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

dihydrocarvone : A dihydrocarvone resulting from reduction of the endocyclic cyclohexene double bond. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID24473
CHEBI ID23733
SCHEMBL ID309206
MeSH IDM0555999

Synonyms (42)

Synonym
LS-13847
p-menth-8-en-2-one
cyclohexanone, 2-methyl-5-(1-methylethenyl)-
dihydrocarvone
8-p-menthen-2-one
p-menth-8(9)-en-2-one
2-methyl-5-(1-methylethenyl)cyclohexanone
2-methyl-5-(1-methylvinyl)cyclohexan-1-one
einecs 231-857-0
CHEBI:23733
7764-50-3
2-methyl-5-(prop-1-en-2-yl)cyclohexanone
menth-8-en-2-one
2-methyl-5-isopropenylcyclohexanone
5-isopropenyl-2-methylcyclohexanone
2-methyl-5-prop-1-en-2-ylcyclohexan-1-one
C18018
2-methyl-5-(prop-1-en-2-yl)cyclohexan-1-one
unii-yqs5cw1o1j
3-isopropenyl-6-methylcyclohexanone
yqs5cw1o1j ,
dihydrocarvone, (+)-
FT-0624469
AKOS015907251
SCHEMBL309206
AZOCECCLWFDTAP-UHFFFAOYSA-N
5-isopropenyl-2-methylcyclohexanone #
W-104306
1,6-dihydrocarvone
cyclohexanone,2-methyl-5-(1-methylethenyl)-
mfcd00001636
2-methyl-5-(1-methylethenyl)-cyclohexanone
2-methyl-5-(1-methylethenyl)cyclohexanone, 9ci
fema 3565
FT-0773968
DTXSID00863556
E76541
Q27109809
BCP30885
a dihydrocarvone
an isodihydrocarvone
CS-0031698
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
dihydrocarvonesAny carvone having one of its C=C double bonds reduced.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (15)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (66.67)24.3611
2020's5 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.89

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.89 (24.57)
Research Supply Index2.77 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index42.09 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.89)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (13.33%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (86.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1,2-dipalmitoylphosphatidylcholine
1,2-Dipalmitoylphosphatidylcholine: Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.		2.1310
carveol
carveol: structure given in first source; prolongs tumor latency and decreases tumor yield. carveol : A limonene monoterpenoid that is cyclohex-2-en-1-ol substituted by a methyl group at position 2 and a prop-1-en-2-yl group at position 5.		3.5110limonene monoterpenoidplant metabolite;
volatile oil component
carvone
carvone: an oxidized derivative of limonene; RN given refers to cpd without isomeric designation; L-carvone has spearmint flavor, D-carvone has dill/caraway flavor. carvone : A p-menthane monoterpenoid that consists of cyclohex-2-enone having methyl and isopropenyl substituents at positions 2 and 5, respectively.		4.5560botanical anti-fungal agent;
carvones		allergen
cyclohexanol
Cyclohexanols: Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers.. cyclohexanols : An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton.		2.1110cyclohexanols;
secondary alcohol		solvent
caprolactone
hexano-6-lactone : A epsilon-lactone that is oxepane substituted by an oxo group at position 2.		2.2110epsilon-lactone
myrtenol
myrtenol: fragrance ingredient; structure in first source		2.0810
limonene
Limonene: A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).. limonene : A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively.		7.7620cycloalkene;
p-menthadiene		human metabolite
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		2.1710metal allergen;
nickel group element atom;
platinum group metal atom
myrtenal
myrtenal: RN refers to cpd without isomeric designation; structure given in first source		2.0810
beta-thujone
[no description available]		2.1310beta-thujone
stannane
[no description available]		2.1710mononuclear parent hydride;
tin hydride
nadp
[no description available]		2.2510
mutilin
mutilin: structure in first source		2.0810
ConditionIndicatedRelationship StrengthStudiesTrials