deoxynupharidine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

deoxynupharidine: RN given refers to (1alpha,4beta,7beta,9aalpha,1R)-isomer; structure. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	442525
CHEMBL ID	140758
CHEBI ID	4427
SCHEMBL ID	11690224
MeSH ID	M0056795

Synonyms (9)

Synonym
C09945 ,
1143-54-0
deoxynupharidine
chebi:4427 ,
CHEMBL140758 ,
(1r,4s,7s,9as)-4-(furan-3-yl)-1,7-dimethyl-2,3,4,6,7,8,9,9a-octahydro-1h-quinolizine
SCHEMBL11690224
DTXSID50921312
Q27106378

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
quinolizines
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (5)

Assay ID	Title	Year	Journal	Article
AID39280	Inhibition of invasion of B16 melanoma cells by 0.1 uM concentration of the compound	2003	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 13, Issue:24	Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
AID39279	Inhibition of invasion of B16 melanoma cells by 0.01 uM concentration of the compound; ND=No data	2003	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 13, Issue:24	Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
AID39282	Inhibition of invasion of B16 melanoma cells by 10 uM concentration of the compound	2003	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 13, Issue:24	Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
AID39283	Inhibition of invasion of B16 melanoma cells by 1 uM concentration of the compound	2003	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 13, Issue:24	Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
AID39281	Inhibition of invasion of B16 melanoma cells by 100 uM concentration of the compound	2003	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 13, Issue:24	Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (44.44)	18.7374
1990's	1 (11.11)	18.2507
2000's	3 (33.33)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
piperidine [no description available]	2.02	1	azacycloalkane; piperidines; saturated organic heteromonocyclic parent; secondary amine	base; catalyst; human metabolite; non-polar solvent; plant metabolite; protic solvent; reagent
palladium Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.	2.42	2	metal allergen; nickel group element atom; platinum group metal atom
indium Indium: A metallic element, atomic number 49, atomic weight 114.818, symbol In. It is named from its blue line in the spectrum.. indium atom : A metallic element first identified and named from the brilliant indigo (Latin indicum) blue line in its flame spectrum.	2.11	1	boron group element atom
piperidines Piperidines: A family of hexahydropyridines.	2.42	2

Condition	Relationship Strength	Studies
Cancer of Lung [description not available]	2.01	1
B16 Melanoma [description not available]	2.01	1
Metastase [description not available]	2.01	1
Invasiveness, Neoplasm [description not available]	2.01	1
Lung Neoplasms Tumors or cancer of the LUNG.	2.01	1
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	2.01	1
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	1.96	1

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