berefrine: oxazolidine prodrug of phenylephrine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
---|---|
PubMed CID | 60017 |
SCHEMBL ID | 10527149 |
MeSH ID | M0144907 |
Synonym |
---|
berefrine (usan/inn) |
D03097 |
105567-83-7 |
berefrine |
AKOS022659480 |
SCHEMBL10527149 |
DTXSID10869448 |
Excerpt | Reference | Relevance |
---|---|---|
" The pharmacokinetic parameters, apparent absorption, and elimination rate constants, of phenylephrine and the prodrug were determined from aqueous humor concentration-time and mydriasis-time profiles." | ( Ocular pharmacokinetics and pharmacodynamics of phenylephrine and phenylephrine oxazolidine in rabbit eyes. Chien, DS; Schoenwald, RD, 1990) | 0.28 |
Excerpt | Relevance | Reference |
---|---|---|
" A dosing volume of 10 microliter was instilled into rabbit eyes and the pupillary diameter was measured over time." | ( Improving the ocular absorption of phenylephrine. Chien, DS; Schoenwald, RD, ) | 0.13 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.68) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 1 (16.67%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (83.33%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |