Compounds > 3,12-dihydroxy-5-cholenoic acid
Page last updated: 2024-11-10

3,12-dihydroxy-5-cholenoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3,12-dihydroxy-5-cholenoic acid: unusual bile acid found in human biological fluids; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5283979
CHEBI ID184516
SCHEMBL ID23923767
MeSH IDM0150607

Synonyms (14)

Synonym
LMST04010219 ,
3beta,12alpha-dihydroxychol-5-en-24-oic acid
(4r)-4-[(3s,8r,9s,10r,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoic acid
3beta,12alpha-dihydroxychol-5-enoic acid
chol-5-en-24-oic acid, 3,12-dihydroxy-, (3beta,12alpha)-
3,12-dhcoa
3,12-dihydroxy-5-cholenoic acid
3-beta,12-alpha-dihydroxy-5-cholen-24-oic acid
63266-92-2
3,12-dihydroxychol-5-en-24-oic acid
3beta,12alpha-dihydroxy-5-cholen-24-oic acid
DTXSID60979324
SCHEMBL23923767
CHEBI:184516
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
cholanoid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.34 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.34)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
deoxycholic acid
Deoxycholic Acid: A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.. deoxycholic acid : A bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively.		2.0210bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
bilirubin
[no description available]		1.9710biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Liver Dysfunction
[description not available]		02.6630
Liver Diseases
Pathological processes of the LIVER.		02.6630
Biliary Tract Diseases
Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.		01.9710