Compounds > 2-trifluoromethylbenzoic acid
Page last updated: 2024-11-05

2-trifluoromethylbenzoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID9899
CHEBI ID60694
SCHEMBL ID221518
MeSH IDM0190796

Synonyms (57)

Synonym
nsc-88326
nsc88326
433-97-6
o-carboxybenzotrifluoride
.alpha.,.alpha.,.alpha.-trifluoro-o-toluic acid
2-trifluoromethylbenzoic acid
ENAMINE_005364
NCIOPEN2_001264
2-(trifluoromethyl)benzoic acid, 98%
2-(trifluoromethyl)benzoic acid ,
AC-2625
AKOS000118808
HMS1409D18
CHEBI:60694
o-(trifluoromethyl)benzoic acid
2-tfmba
o-trifluoromethylbenzoic acid
2-(trifluoroformyl)benzoic acid
ortho-(trifluoromethyl)benzoic acid
o-(trifluoroformyl)benzoic acid
FT-0695424
T1302
alpha,alpha,alpha-trifluoro-o-toluic acid
137938-95-5
trifluoromethylbenzoic acid
2-trifluromethylbenzoic acid
STK946190
nsc 88326
benzoic acid, 2-(trifluoromethyl)-
unii-0r1ck7mzua
0r1ck7mzua ,
einecs 207-093-9
FT-0608957
AM61555
SCHEMBL221518
o-toluic acid, .alpha.,.alpha.,.alpha.-trifluoro-
mfcd00002476
SY002327
2-trifluoromethyl-benzoic acid
ortho-trifluoromethylbenzoic acid
o-trifluoromethyl-benzoic acid
2-trifluoromethyl benzoic acid
W-106233
BS-4039
benzoic acid,(trifluoromethyl)-
F2191-0057
Z56922112
2-(trifluoromethyl)benzoicacid
Q27128431
CS-W015913
DTXSID90870537
EN300-17349
AC7509
o-toluic acid, ?,?,?-trifluoro- (6ci,7ci,8ci); 2-(trifluoromethyl)benzoic acid; nsc 88326; o-(trifluoromethyl)benzoic acid; ?,?,?-trifluoro-o-toluic acid
A913683
2-(trifluoromethyl)benzoic;a,a,a-trifluoro-o-toluic acid;alpha,alpha,alpha-trifluoro-o-toluic acid
jpcuzpkblyuqrd-uhfffaoysa-n
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
benzoic acidsAny aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group.
(trifluoromethyl)benzenesAn organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.76

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.76 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.76)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
bromide
Bromides: Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)		2.1710halide anion;
monoatomic bromine
toluene
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.		2.9440methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
2,6-difluorobenzoic acid
2,6-difluorobenzoic acid: structure given in first source		2.1710
4-(trifluoromethyl)benzoic acid
4-trifluoromethylbenzoic acid : A benzoic acid carrying a 4-trifluoromethyl substituent.		1.9710(trifluoromethyl)benzenes;
benzoic acids
4-fluorobenzoic acid
[no description available]		1.9710fluorobenzoic acidbacterial xenobiotic metabolite
pentafluorobenzoic acid
[no description available]		2.1710perfluorinated compound
fluorine
Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.		1.9710diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
potassium bromide
potassium bromide : A metal bromide salt with a K(+) counterion.		2.1710potassium salt
3-trifluoromethylbenzoate
3-trifluoromethylbenzoate: RN given refers to unlabeled parent cpd		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio
[description not available]		02.0610
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)		02.0610