1,1,1-trifluoro-2-iodoethane

Description

1,1,1-trifluoro-2-iodoethane is an organofluorine compound with the chemical formula CH₂FI₃. It's a colorless liquid with a pungent odor.

**Importance in Research:**

While it's not widely known, 1,1,1-trifluoro-2-iodoethane is a potentially interesting molecule for research due to its unique properties:

* **Fluorination:** The presence of three fluorine atoms on one carbon atom significantly affects its reactivity and properties. Fluorine is the most electronegative element, making the carbon atom electron-deficient and susceptible to nucleophilic attack.
* **Iodination:** The iodine atom makes it a good substrate for reactions involving iodine-containing reagents or radical reactions.
* **Chirality:** The molecule is chiral, meaning it exists in two enantiomeric forms (mirror images). This opens up opportunities to study stereochemistry and enantioselective reactions.

**Potential Applications:**

The combination of fluorine and iodine makes this compound potentially useful in various areas of research, including:

* **Organic Synthesis:** It can be used as a building block for the synthesis of other fluorinated compounds, which are often found in pharmaceuticals, agrochemicals, and materials science.
* **Medicinal Chemistry:** Fluorine substitution can improve the pharmacokinetic properties of drugs, such as increased metabolic stability and improved bioavailability.
* **Materials Science:** Fluorine often imparts hydrophobic and oleophobic properties to materials, making them useful in coatings, membranes, and other applications.

**Challenges and Safety:**

1,1,1-trifluoro-2-iodoethane is a relatively unexplored compound, and its synthesis and handling require careful attention to safety due to the potential for toxicity and reactivity.

**Overall:**

1,1,1-trifluoro-2-iodoethane is a promising molecule for research with potential applications in various fields. Further investigation into its synthesis, reactivity, and properties could lead to new discoveries and advancements.

1,1,1-trifluoro-2-iodoethane: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]