suillin: isol from Suillus granulatus; structure given in first source [MeSH]
Suillin : no description available [CHeBI]
| ID Source | ID |
|---|---|
| PubMed CID | 5387599 |
| CHEMBL ID | 485467 |
| CHEBI ID | 190366 |
| MeSH ID | M0170860 |
| Synonym |
|---|
| NSC625110 , |
| suillin |
| nsc-625110 |
| 1,4-benzenetriol, 3-(3,7,11,15-tetramethyl)-2,6,10,14-hexadecatetraenyl)- 4-acetate, (e,e,e)- |
| 103538-03-0 |
| [3,4-dihydroxy-2-[(2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]phenyl] acetate |
| 1,2,4-benzenetriol, 3-(3,7,11,15-tetramethyl)-2,6,10, 14-hexadecatetraenyl)- 4-acetate, (e,e,e)- |
| 3,4-dihydroxy-2-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)phenyl acetate |
| CHEMBL485467 |
| tetraprenylphenolsuillin |
| 1,2,4-benzenetriol, 3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, 4-acetate, (e,e,e)- |
| 4-acetoxy-3-geranylgeranyl-1,2-dihydroxybenzene |
| CHEBI:190366 |
| unii-v324ra58sa |
| nsc 625110 |
| v324ra58sa , |
| 1,2,4-benzenetriol, 3-[(2e,6e,10e)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-, 4-acetate |
| Class | Description |
|---|---|
| diterpenoid | Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID359654 | Cytotoxicity against human KB cells after 72 hrs by MTT assay | 1992 | Journal of natural products, Dec, Volume: 55, Issue:12 ISSN: 0163-3864 | Cytotoxic activity of tetraprenylphenols related to suillin, an antitumor principle from Suillus granulatus. |
| AID359657 | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay | 1992 | Journal of natural products, Dec, Volume: 55, Issue:12 ISSN: 0163-3864 | Cytotoxic activity of tetraprenylphenols related to suillin, an antitumor principle from Suillus granulatus. |
| AID336908 | Cytotoxicity against human NSCLC-N6 cells | Journal of natural products, , Volume: 52, Issue:4 ISSN: 0163-3864 | An antitumor principle from Suillus granulatus. | |
| AID336906 | Cytotoxicity against human KB cells | Journal of natural products, , Volume: 52, Issue:4 ISSN: 0163-3864 | An antitumor principle from Suillus granulatus. | |
| AID336907 | Cytotoxicity against mouse P388 cells | Journal of natural products, , Volume: 52, Issue:4 ISSN: 0163-3864 | An antitumor principle from Suillus granulatus. | |
| AID336910 | In vivo antitumor activity against mouse P388 cells at 10 mg/kg, ip administered on 1,5 and 9 days relative to control | Journal of natural products, , Volume: 52, Issue:4 ISSN: 0163-3864 | An antitumor principle from Suillus granulatus. | |
| AID359659 | Cytotoxicity against human NSCLC-N6 cells after 72 hrs by MTT assay | 1992 | Journal of natural products, Dec, Volume: 55, Issue:12 ISSN: 0163-3864 | Cytotoxic activity of tetraprenylphenols related to suillin, an antitumor principle from Suillus granulatus. |
| AID336909 | In vivo antitumor activity against mouse P388 cells at 5 mg/kg, ip administered on 1,5 and 9 days relative to control | Journal of natural products, , Volume: 52, Issue:4 ISSN: 0163-3864 | An antitumor principle from Suillus granulatus. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ergosterol | 3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols | fungal metabolite; Saccharomyces cerevisiae metabolite | 2017 | 2017 | 7.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
| cytochrome c-t | 2016 | 2016 | 8.0 | high | 0 | 0 | 0 | 0 | 1 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cancer of Liver | 0 | 2014 | 2014 | 10.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Carcinoma, Hepatocellular | 0 | 2014 | 2014 | 10.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Carcinoma, Non-Small Cell Lung | 0 | 2021 | 2021 | 3.0 | medium | 0 | 0 | 0 | 0 | 0 | 1 | |
| Carcinoma, Non-Small-Cell Lung | 0 | 2021 | 2021 | 3.0 | medium | 0 | 0 | 0 | 0 | 0 | 1 | |
| Carcinoma, Small Cell Lung | 0 | 2016 | 2016 | 8.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Hepatocellular Carcinoma | 0 | 2014 | 2014 | 10.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Leukemia P388 | 0 | 1992 | 1992 | 32.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 | |
| Liver Neoplasms | 0 | 2014 | 2014 | 10.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Small Cell Lung Carcinoma | 0 | 2016 | 2016 | 8.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |