D-aspartate transmembrane transporter activity

Definition

Target type: molecularfunction

Enables the transfer of D-aspartate from one side of a membrane to the other. [GO_REF:0000070, PMID:7914198]

D-aspartate transmembrane transporter activity is a molecular function that describes the ability of a protein to facilitate the movement of the amino acid D-aspartate across cell membranes. D-aspartate is a stereoisomer of the more common L-aspartate, and it plays a role in various cellular processes, including neurotransmission and signal transduction.

The transport of D-aspartate across the cell membrane is typically mediated by specific transporter proteins, which act as gatekeepers, allowing selective passage of D-aspartate while restricting the movement of other molecules. These transporters often employ various mechanisms to ensure efficient and regulated transport, including active transport, which utilizes energy to move D-aspartate against its concentration gradient, and passive transport, which relies on the concentration difference across the membrane to drive movement.

D-aspartate transporters are crucial for maintaining cellular homeostasis by regulating the intracellular concentration of D-aspartate. This regulation is essential for proper cellular function, as imbalances in D-aspartate levels can lead to disruptions in various cellular processes.

The specific molecular mechanisms employed by D-aspartate transporters vary depending on the transporter protein involved. Some transporters may utilize binding sites to recognize and interact with D-aspartate molecules, while others may rely on conformational changes to facilitate transport.

The understanding of D-aspartate transmembrane transporter activity is crucial for understanding the role of D-aspartate in cellular processes and its potential implications in various physiological and pathological conditions. The study of these transporters can shed light on the mechanisms of D-aspartate transport, the regulation of D-aspartate levels, and the potential targets for therapeutic interventions.'
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Proteins (1)

Compounds (13)