| Assay ID | Title | Year | Journal | Article |
|---|
| AID71166 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID348021 | Activity at human EAAT3 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID71168 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID328864 | Inhibition of [3H]L-aspartate uptake at Pyrococcus horikoshii sodium-coupled aspartate transporter after 3 mins | 2007 | Nature, Jan-25, Volume: 445, Issue:7126
| Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. |
| AID339902 | Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assay | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID339906 | Inhibition of glutamate-induced depolarization in human EAAT3 expressed in HEK293 cells by FMP assay | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID1725867 | Inhibition of human EAAT3 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillation counting analysis | 2020 | ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
| β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs). |
| AID71165 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 1 (EAAT1) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID1725862 | Inhibition of rat EAAT4 transfected in human tsA201 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillation counting analysis | 2020 | ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
| β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs). |
| AID339905 | Inhibition of glutamate-induced depolarization in human EAAT2 expressed in HEK293 cells by FMP assay | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID348013 | Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID348015 | Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID1725865 | Inhibition of human EAAT1 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillation counting analysis | 2020 | ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
| β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs). |
| AID348014 | Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID1725866 | Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillation counting analysis | 2020 | ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
| β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs). |
| AID348020 | Activity at human EAAT2 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID348019 | Activity at human EAAT1 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | 2009 | Journal of medicinal chemistry, Feb-26, Volume: 52, Issue:4
| Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. |
| AID71158 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID328868 | Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter D405N mutant in presence of NaCl | 2007 | Nature, Jan-25, Volume: 445, Issue:7126
| Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. |
| AID71167 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71160 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71169 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71162 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71164 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 1 (EAAT1) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |