Target type: molecularfunction
Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. [GOC:mah]
Oligosaccharide binding is a molecular function that involves the interaction of a protein or other molecule with an oligosaccharide. Oligosaccharides are complex carbohydrates composed of multiple sugar monomers linked together. This interaction is crucial for a wide range of biological processes, including cell adhesion, signaling, and recognition. The binding of an oligosaccharide to a protein can trigger a variety of downstream events, such as changes in protein conformation, activation of signaling pathways, or the recruitment of other proteins. Oligosaccharide binding can be mediated by a variety of different mechanisms, including hydrogen bonding, van der Waals interactions, and electrostatic interactions. The specificity of oligosaccharide binding is often determined by the arrangement of the sugar monomers in the oligosaccharide, as well as the amino acid residues in the binding site of the protein. This specificity allows cells to differentiate between different types of oligosaccharides, which is essential for their ability to respond to specific signals or to interact with other cells in a controlled manner.'
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| Protein | Definition | Taxonomy |
|---|---|---|
| Lysyl oxidase homolog 2 | A lysyl oxidase homolog 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9Y4K0] | Homo sapiens (human) |
| E-selectin | An E-selectin that is encoded in the genome of human. [PRO:WCB, UniProtKB:P16581] | Homo sapiens (human) |
| P-selectin | A P-selectin that is encoded in the genome of human. [PRO:WCB, UniProtKB:P16109] | Homo sapiens (human) |
| L-selectin | An L-selectin that is encoded in the genome of human. [PRO:JAN, UniProtKB:P14151] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| gallic acid | gallate : A trihydroxybenzoate that is the conjugate base of gallic acid. | trihydroxybenzoic acid | antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite |
| phenethylamine | 2-phenylethylamine : A phenylethylamine having the phenyl substituent at the 2-position. phenethylamine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7016 | alkaloid; aralkylamine; phenylethylamine | Escherichia coli metabolite; human metabolite; mouse metabolite |
| pyrithione | pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure | monohydroxypyridine; pyridinethione | ionophore |
| aminopropionitrile | Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid. | aminopropionitrile | antineoplastic agent; antirheumatic drug; collagen cross-linking inhibitor; plant metabolite |
| disulfiram | organic disulfide; organosulfur acaricide | angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 3.1.1.1 (carboxylesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; ferroptosis inducer; fungicide; NF-kappaB inhibitor | |
| thiram | thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations. | organic disulfide | antibacterial drug; antifungal agrochemical; antiseptic drug |
| benzylamine | aminotoluene : Any member of the class of toluenes carrying one or more amino groups. | aralkylamine; primary amine | allergen; EC 3.5.5.1 (nitrilase) inhibitor; plant metabolite |
| oxycinchophen | quinolines | ||
| 2,3,4-Trihydroxybenzoic acid | hydroxybenzoic acid | ||
| 4-nitrobenzylamine | 4-nitrobenzylamine: RN given refers to parent cpd | ||
| 4-fluorobenzylamine | |||
| 4-pyridylmethylamine | 4-pyridylmethylamine: structure given in first source | ||
| sulfoquinovosyl dipalmitoyl glyceride | sulfoquinovosyl dipalmitoyl glyceride: P-selectin receptor inhibitor; isolated from the alga Dictyochloris fragrans; structure in first source | ||
| pd 144795 | |||
| bimosiamose | bimosiamose: a selectin inhibitor | ||
| 4-[(4-methylphenyl)thio]-2-thieno[2,3-c]pyridinecarboxamide | aryl sulfide | ||
| psi 697 | 2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo(H)quinoline-4-carboxylic acid: inhibitor of P selectin that decreases vein wall injury in a rat stenosis model of venous thrombosis | ||
| galactocerebroside | galactocerebroside: a NITROGEN containing sphingolipid |