D-aspartate transmembrane transport

Definition

Target type: biologicalprocess

The process in which D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore. [GOC:mah, GOC:rph]

D-aspartate transmembrane transport is a crucial process that involves the movement of D-aspartate, a non-proteinogenic amino acid, across cellular membranes. This transport is mediated by specific membrane proteins known as D-aspartate transporters. These transporters facilitate the passage of D-aspartate from one side of the membrane to the other, often against a concentration gradient. The exact mechanism of D-aspartate transport varies depending on the transporter involved, but it typically involves a combination of conformational changes and interactions with the substrate. Some D-aspartate transporters may utilize active transport, requiring energy expenditure to move D-aspartate against its concentration gradient. Others may rely on passive transport, facilitated by the concentration gradient. The process of D-aspartate transmembrane transport plays a vital role in various physiological functions. It is involved in maintaining D-aspartate homeostasis, regulating neurotransmission, and contributing to the overall cellular metabolism of D-aspartate. This amino acid has been implicated in diverse biological processes, including brain function, neuronal plasticity, and endocrine regulation. D-aspartate transport also plays a role in the pathogenesis of certain diseases, such as neurodegenerative disorders and metabolic diseases. Further research is needed to fully elucidate the intricate mechanisms of D-aspartate transmembrane transport and its implications for human health.'
"

Proteins (1)

Compounds (13)